55265-53-7

Basic information

• Product Name: 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXAMIDE
• Synonyms: 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXAMIDE;Cyclopropanecarboxamide, 2,2,3,3-tetramethyl- (9CI);CyclopropanecarboxaMide, 2,2,3,3-tetraMethyl-
• CAS NO: 55265-53-7
• Molecular Formula: C8H15NO
• Molecular Weight: 141.2108
• Product Categories: AMIDE
• Mol File: 55265-53-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 231.1 °C at 760 mmHg
• Flash Point: 93.5 °C
• Appearance: /
• Density: 0.95 g/cm³
• Vapor Pressure: 0.0636mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXAMIDE(55265-53-7)
• EPA Substance Registry System: 2,2,3,3-TETRAMETHYLCYCLOPROPANECARBOXAMIDE(55265-53-7)

Safety Data

• Hazardous Substances Data: 55265-53-7(Hazardous Substances Data)

Usage

General Description

2,2,3,3-Tetramethylcyclopropanecarboxamide, also known as TMCCA, is a chemical compound with a molecular formula C9H17NO. It is a cyclopropanecarboxamide derivative that is commonly used as a rubber antioxidant and a stabilizer for plastics and elastomers. TMCCA is known for its high thermal stability and effectiveness in preventing degradation and discoloration of polymers. It is also used as an intermediate in the production of pharmaceuticals and agrochemicals. TMCCA is a clear, colorless liquid with a faint ammonia-like odor and is classified as a non-hazardous substance under normal handling and use conditions.

InChI:InChI=1/C8H15NO/c1-7(2)5(6(9)10)8(7,3)4/h5H,1-4H3,(H2,9,10)

Upstream product

• 15641-58-4 2,2,3,3-tetramethylcyclopropane-1-carboxylic acid 
• 24303-61-5 2,2,3,3-tetramethylcyclopropanecarbonyl chloride 

Downstream Products

• 67358-15-0 2,2,3,3-tetramethylcyclopropanemethylamine 

Relevant articles and documents

Facile synthesis of amide and amine derivatives of 2,2,3,3- tetramethylcyclopropanecarboxylic acid

An efficient one-pot procedure for the synthesis of amide derivatives of 2,2,3,3-tetramethylpropanecarboxylic acid (TMCA) that involves the treating of TMCA in A/,A/-dimethylacetamide (DMAC) with thionyl chloride and stoichiometric amounts of reactant ami

Derivatives of tetramethylcyclopropane

The present invention relates to derivatives of 2,2,3,3-tetramethylcyclopropane carboxylic acid (TMCA) of general formula (I), STR1 wherein R is lower alkyl group (C1 -C6), an aryl group, an aralkyl group or an amide of general formula (II), STR2 where R1 and R2 are the same or different and may be hydrogen, a alkyl group (C1 -C6), an aryl group or an aralkyl group, and n=0-3, to their racemic mixtures and the D and L enantiomers. The invention also relates to processes for the preparation of said compounds and for pharmaceutical preparations comprising the same. The new compounds show improved activity against epilepsy.

Branched amides of L-aspartyl-D-amino acid dipeptides

Amides of L-aspartyl-D-amino acid dipeptides of the formula STR1 and physiologically acceptable cationic and acid addition salts thereof wherein Ra is CH2 OH or CH2 OCH3 ; R is a branched member selected from the group consisting of fenchyl, diisopropylcarbinyl, d-methyl-t-butylcarbinyl, d-ethyl-t-butylcarbinyl, di-t-butylcarbinyl, 2-methylthio-2,4-dimethylpentan-3-yl, STR2 where at least one of R3, R4, R5, R6 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms, X is O, S, SO, SO2, C=O or CHOH; m is zero or 1-4, n and p are each zero, 1, 2 or 3 where the sum of n+p is not greater than 3 and the sum of the carbon atoms in R3, R4, R5 and R6 is not greater than six, and when both of R3 and R4 or R5 and R6 are alkyl they are methyl or ethyl, STR3 where one of R7, R8, R9 is alkyl having from one to four carbon atoms and the remainder are hydrogen or alkyl having from one to four carbon atoms and the sum of the carbon atoms in R7, R8 and R9 is not greater than six, m and q are the same or different and each have the values previously defined for m; STR4 where each of R12 and R13 are methyl or ethyl, or R12 is hydrogen and R13 is alkyl having from one to four carbon atoms, Z is O or NH and t is 1 or 2, STR5 where W is 1-4, R14 and R16 are each alkyl having from one to four carbon atoms, R15 is H, OH, methyl or ethyl and the sum of the carbon atoms in R14, R15 and R16 is not greater than six and when both of R14 and R15 are alkyl they are methyl or ethyl, and STR6 where R17 and R19 are alkyl having from one to four carbon atoms, R18 and R20 are H or alkyl having one to two carbon atoms, A is OH and B is H, OH or CH3 and taken together A and B are STR7 where the sum of the carbon atoms in R17, R18, R19 and R20 is not greater than six and when both of R17 and R18 or R19 and R20 are alkyl they are methyl or ethyl; said amides are potent sweeteners having advantages over the prior art, edible compositions containing them, methods for their use in edible compositions and novel amide intermediates useful in their production.