55266-18-7

Usage

Uses

1. Used in Pharmaceutical Applications:
Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride is used as a therapeutic agent for its protective properties against oxidative stress and peroxynitrite-induced damage. Its application is particularly relevant in conditions where oxidative stress plays a significant role, such as in various diseases and disorders.
2. Used in Research and Development:
MnTBAP chloride is utilized as a research tool in the study of oxidative stress, superoxide dismutase function, and peroxynitrite-mediated cellular processes. It helps researchers understand the mechanisms of oxidative stress and develop new therapeutic strategies to combat its effects.
3. Used in Drug Delivery Systems:
Mn(III) Meso-Tetra (4-carboxyphenyl) porphine chloride can be employed in the development of drug delivery systems to enhance its bioavailability and therapeutic outcomes. By incorporating MnTBAP into various carriers, such as organic and metallic nanoparticles, its delivery and efficacy can be improved, making it a more effective agent in treating conditions associated with oxidative stress.

Biochem/physiol Actions

Cell permeable: yes

References

1) Szabo et al. (1996), Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial resporation in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger; FEBS Lett., 381 82 2) Faulkner et al. (1994), Stable MN(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo; J. Biol. Chem., 269 23471