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7-methyl[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one is a heterocyclic compound characterized by a triazole fused to a pyridine ring, with a methyl group attached at the 7th position. This chemical structure is notable for its potential applications in medicinal chemistry, particularly as a building block for the synthesis of various biologically active molecules. The compound's unique arrangement of nitrogen and carbon atoms in the ring system contributes to its stability and reactivity, which can be exploited in the design of new drugs and pharmaceuticals. Its chemical properties, such as solubility and reactivity, can be influenced by the presence of the methyl group and the overall structure, making it a versatile component in organic synthesis.

5528-57-4

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5528-57-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5528-57-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,2 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5528-57:
(6*5)+(5*5)+(4*2)+(3*8)+(2*5)+(1*7)=104
104 % 10 = 4
So 5528-57-4 is a valid CAS Registry Number.

5528-57-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-methyl-2H-[1,2,4]triazolo[4,3-a]pyridin-3-one

1.2 Other means of identification

Product number -
Other names 7-Methyl-s-triazolo<4,3-a>pyridin-3-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5528-57-4 SDS

5528-57-4Downstream Products

5528-57-4Relevant academic research and scientific papers

GPR139 RECEPTOR MODULATORS

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Page/Page column 216, (2020/06/01)

Compounds are provided that modulate the GPR139 receptor, compositions containing the same, and to methods of their preparation and use for treatment of a malcondition wherein modulation of the GPR139 receptor is medically indicated or beneficial. Such compounds have the structure of Formula (X) or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein R1, R2, R3, R4, R9, R10, R11, and R12, Q5, Q6, Q7 and Q8 are as defined herein.

The Base-Promoted Annulation of 2-Hydrazinyl Pyridine and CO2 toward Triazolones

Wu, Xiaopeng,Sun, Song,Wang, Bingbing,Cheng, Jiang

supporting information, p. 3855 - 3859 (2017/11/15)

A base-promoted annulation of 2-hydrazinyl pyridine and atmospheric pressure of CO2 has been developed in the presence of silane as reducing reagent, affording a series of triazolones in moderate to excellent yields. CO2 served as a carbonyl source in this transfomation. Moreover, benzamidrazones also worked well under this procedure. Thus, it represents a green, sustainable and straightforward pathway to access triazolone frameworks. (Figure presented.).

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