552819-77-9Relevant academic research and scientific papers
Convenient synthesis of quinoline-fused triazolo-azepine/oxepine derivatives through Pd-catalyzed C-H functionalisation of triazoles
Mahesh, Kukkamudi,Ravi, Kanakaraju,Rathod, Praveen Kumar,Leelavathi, Panaganti
, p. 2367 - 2373 (2020/02/20)
The efficient and convenient synthesis of a new fused heterocyclic scaffold comprising three different heterocycles, viz., quinolines, azepines/oxepines and triazoles is reported from quinoline-tethered triazoles. The quinoline-tethered triazoles were eas
Intramolecular Heck reaction: A facile sequential one-pot synthesis of 1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridines
Bharath Kumar Reddy, Puchakayala,Ravi, Kanakaraju,Mahesh, Kukkamudi,Leelavathi, Panaganti
, p. 4039 - 4043 (2018/10/09)
A simple and convenient sequential one-pot synthesis of 1,2,3,4-tetrahydrobenzo[b][1,6] naphthyridines has been developed. The reductive amination of 2-chloro-3-formylquinolines with various amines in the presence of sodium borohydride provided the corresponding secondary amines in high yields. Further, a sequential one-pot reaction involving N-allylation and intramolecular Heck type 6-exo-trig cyclization was performed on the secondary amines to afford a range of desired 1,2,3,4-tetrahydrobenzo[b][1,6]-naphthyridine derivatives in good to high yields.
Synthesis and in-vitro antimicrobial activity of secondary and tertiary amines containing 2-chloro-6-methylquinoline moiety
Kumar, Suresh,Bawa, Sandhya,Kaushik, Darpan,Panda, Bibhu P.
, p. 474 - 480 (2012/01/19)
A number of secondary and tertiary amines bearing 2-chloro-6- methylquinoline were synthesized by nucleophilic substitution reaction of 3-(chloromethyl)-2-chloro-6-methylquinoline with substituted aromatic primary and secondary amines in presence of catal
