552833-13-3Relevant academic research and scientific papers
Total Synthesis of the Eight Diastereomers of the Syn-Anti-Syn Phytoprostanes F1 Types I and II
El Fangour, Siham,Guy, Alexandre,Despres, Valerie,Vidal, Jean-Pierre,Rossi, Jean-Claude,Durand, Thierry
, p. 2498 - 2503 (2007/10/03)
Syntheses of the eight enantiomerically pure diastereomers of the syn-anti-syn phytoprostanes F1 types I and II are described starting from D- and L-glucose. Key steps include Wittig coupling, Horner Wadsworth Emmons (HWE) reactions, and enantioselective reduction of α,β -unsaturated ketones.
Radical cyclization; towards the syntheses of tetranor metabolites of 15-F2t-isoprostane
Durand, Thierry,Henry, Olivier,Guy, Alexandre,Roland, Arlène,Vidal, Jean-Pierre,Rossi, Jean-Claude
, p. 2485 - 2495 (2007/10/03)
Radical cyclization of acyclic 1-substituted-2,4-dihydroxylated 5-hexenyl radicals produced functionalized cyclopentane derivatives. These cyclopentanic precursors after different protection/deprotection reactions followed by Wittig and Horner-Wadsworth-E
