552887-05-5Relevant articles and documents
Solid-phase library synthesis of reversed-statine type inhibitors of the malarial aspartyl proteases plasmepsin I and II
Dahlgren, Anders,Kvarnstroem, Ingemar,Vrang, Lotta,Hamelink, Elizabeth,Hallberg, Anders,Rosenquist, Asa,Samuelsson, Bertil
, p. 827 - 841 (2007/10/03)
With the aim to develop inhibitors of the plasmepsin I and II aspartic proteases of the malaria parasite Plasmodium falciparum, we have synthesized sets of libraries from novel reversed-statine isosteres, using a combination of solution phase and solid ph