5529-75-9Relevant academic research and scientific papers
NH-1,2,3-triazole inhibitors of the VIM-2 metallo-β-lactamase
Weide, Timo,Saldanha, S. Adrian,Minond, Dmitriy,Spicer, Timothy P.,Fotsing, Joseph R.,Spaargaren, Michael,Frere, Jean-Marie,Bebrone, Carine,Sharpless, K. Barry,Hodder, Peter S.,Fokin, Valery V.
scheme or table, p. 150 - 154 (2010/10/21)
Metallo-β-lactamases (MBLs) are an emerging cause of bacterial resistance to antibiotic treatment. The VIM-2 β-lactamase is the most commonly encountered MBLs in clinical isolates worldwide. Described here are potent and selective small molecule inhibitor
