55302-96-0

Basic information

• Product Name: 5-[(2-Hydroxyethyl)amino]-o-cresol
• Synonyms: 2-METHYL-5-N-(BETA-HYDROXYETHYL)AMINO PHENOL;2-Methyl-5-N-hydroxyethylamino phenol;2-METHYL-5-HYDROXYETHYLAMINOPHENOL;5-[(2-HYDROXYETHYL)AMINO]-O-CRESOL;5[(2-HYDROXYETHYL)AMINO]-2-METHYL PHENOL;1-methyl-2-hydroxy-4-(beta-hydroxyethyl)aminobenzene;2-hydroxy-4-(beta-hydroxyethyl)aminotoluene;5-((2-hydroxyethyl)amino)-2-methyl-pheno
• CAS NO: 55302-96-0
• Molecular Formula: C₉H₁₃NO₂
• Molecular Weight: 167.21
• EINECS: 259-583-7
• Mol File: 55302-96-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 90-92℃
• Boiling Point: 366 ºC at 760 mmHg
• Flash Point: 181.4 ºC
• Appearance: light brown powder
• Density: 1.215 g/cm³
• Vapor Pressure: 5.32E-06mmHg at 25°C
• Refractive Index: 1.626
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 10.28±0.10(Predicted)
• Water Solubility: 37g/L at 20℃
• CAS DataBase Reference: 5-[(2-Hydroxyethyl)amino]-o-cresol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(2-Hydroxyethyl)amino]-o-cresol(55302-96-0)
• EPA Substance Registry System: 5-[(2-Hydroxyethyl)amino]-o-cresol(55302-96-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RTECS: SL5078600
• Hazardous Substances Data: 55302-96-0(Hazardous Substances Data)

Usage

Chemical Properties

Light brown powder

Flammability and Explosibility

Notclassified

InChI:InChI=1/C9H13NO2/c1-7-2-3-8(6-9(7)12)10-4-5-11/h2-3,6,10-12H,4-5H2,1H3

Upstream product

• 75-21-8 oxirane 
• 2835-95-2 amino-4 hydroxy-2 toluene 

Downstream Products

• 1253977-03-5 1-(2-{[3-({(1E)-2-[(2-hydroxyethyl)-amino]-5-methyl-4-oxocyclohexa-2,5-diene-1-ylidene}amino)pyrazolo[1,5-a]pyridin-2-yl]amino}ethyl)-3-methyl-1H-imidazol-3-ium chloride 
• 1253977-00-2 4-(3-{[(1E)-2-[(2-hydroxyethyl)amino]-5-methyl-4-oxocyclohexa-2,5-dien-1-ylidene]amino}pyrazolo[1,5-a]pyridin-2-yl)-1,1-dimethylpiperazin-1-ium chloride 
• 57240-29-6 2-(Ethyl-{4-[4-hydroxy-2-(2-hydroxy-ethylamino)-5-methyl-phenylamino]-phenyl}-amino)-acetamide 
• 1093946-43-0 3-amino-2-({(1E)-2-[(2-hydroxyethyl)amino]-5-methyl-4-oxocyclohexa-2,5-dien-1-ylidene}amino)-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one 
• 57838-92-3 4-(2-Chloro-4-methylamino-phenylamino)-5-(2-hydroxy-ethylamino)-2-methyl-phenol 
• 56330-76-8 4-[(Z)-2-Chloro-4-methylamino-phenylimino]-5-(2-hydroxy-ethylamino)-2-methyl-cyclohexa-2,5-dienone 
• 55302-79-9 C₂₀H₂₈N₄O₄S 

Relevant articles and documents

Method for preparing 5-(2-hydroxyethyl) amino-o-methylphenol

The invention relates to a method for preparing 5-(2-hydroxyethyl) amino-o-methylphenol, and the method is characterized by comprising the following steps: (1) condensation reaction, to be more specific, condensation reaction of 5-amino-2-methyl phenol and epoxy ethane in the presence of a catalyst in a certain solvent; (2) distillation, to be more specific, reaction liquid vacuum distillation for removal of a solvent to obtain a 5-(2-hydroxyethyl) amino-o-methylphenol crude product; and (3) purification, to be more specific, organic solvent recrystallization of the 5-(2-hydroxyethyl) amino-o-methylphenol crude product to obtain a purified 5-(2-hydroxyethyl) amino-o-methylphenol product. The method has the advantages of improving of product quality and grade, reducing of environmental pollution, reducing of cost, simple operation, clean and environmentally-friendly product production and makes the product more suitable for mass production.