55304-90-0

Basic information

• Product Name: (2,6-Dichloro-3-pyridinyl)methanol
• Synonyms: 3-PyridineMethanol, 2,6-dichloro-;2,6-Dichloro-3-pyridineMethanol, 95%;2,6-Dichloropyridine-3-methanol;(2,6-Dichloropyridin-3-yl);(2,6-Dichloro-3-pyridinyl)methanol;2,6-Dichloro-3-(hydroxyme...;2,6-Dichloro-3-(hydroxyMethyl)pyridine
• CAS NO: 55304-90-0
• Molecular Formula: C₆H₅Cl₂NO
• Molecular Weight: 178.018
• Mol File: 55304-90-0.mol
• Article Data: 15

Chemical Properties

• Melting Point: 67-69°
• Boiling Point: 311.641 °C at 760 mmHg
• Flash Point: 142.276 °C
• Appearance: White or light yellow solid
• Density: 1.479 g/cm³
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 12?+-.0.10(Predicted)
• CAS DataBase Reference: (2,6-Dichloro-3-pyridinyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2,6-Dichloro-3-pyridinyl)methanol(55304-90-0)
• EPA Substance Registry System: (2,6-Dichloro-3-pyridinyl)methanol(55304-90-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 55304-90-0(Hazardous Substances Data)

Usage

General Description

"(2,6-Dichloro-3-pyridinyl)methanol is a chemical compound primarily used in the production of pesticides and other agricultural products. This organic compound, classified as a pyridine derivative, has the chemical formula C6H5Cl2NO. The compound takes the form of a white to yellowish crystalline powder. It is soluble in organic solvents, but not in water. Due to its use in pesticide production, it is important to handle this chemical with care, respecting its potentially harmful effects if inhaled or if it comes into contact with the skin or eyes. It is commonly stored in cool, well-ventilated areas and sealed containers. As a pesticide ingredient, it's used to control pests that harm crops, but its environmental and health impacts need to be carefully monitored."

Upstream product

• 58584-83-1 2,6-dichloronicotinoyl chloride 
• 55366-29-5 3-acetoxymethyl-2,6-dichloro-pyridine 
• 38496-18-3 2,6-dichloropyridine-3-carboxylic acid 
• 2402-78-0 2,6-dichloropyridine 
• 55304-73-9 2,6-dichloro-pyridine-3-carbaldehyde 
• 58584-86-4 ethyl 2,6-dichloronicotinate 

Downstream Products

• 58584-60-4 (2-amino-6-chloro-pyridin-3-yl)-methanol 
• 905961-62-8 (2,6-dichloropyridin-3-yl)methyl toluenesulfonate 
• 41789-37-1 2,6-dichloro-5-pyridylmethyl chloride 
• 55304-73-9 2,6-dichloro-pyridine-3-carbaldehyde 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS

The present disclosure relates generally to compounds useful in treatment of conditions associated with mutant isocitrate dehydrogenase (mt-IDH), particularly mutant IDH1 enzymes. Specifically, the present invention discloses compound of formula (IA), which exhibits inhibitory activity against mutant IDH1 enzymes. Method of treating conditions associated with excessive activity of mutant IDH1 enzymes with such compound is disclosed. Uses thereof, pharmaceutical composition, and kits are also disclosed.

ANTIVIRAL COMPOUNDS

Disclosed herein are new antiviral compounds, together with pharmaceutical compositions that include one or more antiviral compounds, and methods of synthesizing the same. Also disclosed herein are methods of ameliorating and/or treating a paramyxovirus viral infection with one or more small molecule compounds. Examples of paramyxovirus infection include an infection caused by human respiratory syncytial virus (RSV).

PREPARATION OF PHANTASMIDINE AND ANALOGUES THEREOF

Described are methods of synthesizing phantasmidine and analogues thereof from commercially available starting materials. The compounds are useful as pharmacological probes and potential lead compounds for the development of selective nicotinic receptor therapeutics.