55320-83-7

Upstream product

• 95018-69-2 C₁₉H₂₉⁽²⁾HN₂ 
• 104-53-0 3-phenyl-propionaldehyde 
• 95018-61-4 N-Butyl-N'-tert-butyl-N-((E)-4-phenyl-but-1-enyl)-formamidine 

Downstream Products

• 55321-00-1 7-Phenyl-3-hepten-2-on-4-d⁽¹⁾ 

Relevant academic research and scientific papers

α-Amino Carbanions. Preparation, Metalation, and Alkylation of Enamidines. Synthesis of Piperidine and Pyrrolidine Natural Products and Homologation of Carbonyl Compounds

Saturated heterocycles, as their tert-butylformamidines, may be transformed into enamidines, by metalation-selenation-elimination.These enamidines are valuable precursors to 2-substituted, 2,4-disubstituted, and 2,4,6-trisubstituted pyrrolidines, piperidines, and perhydroazepines, prepared in a regiospecific manner.The method is demonstrated by the synthsesis of selenopsin A and the red fire ant venom.The use of acyclic enamidines is displayed as a homologation reagent which converts carbonyl compounds to higher alkyl derivatives.