55330-74-0Relevant academic research and scientific papers
N-(2-Phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamides containing various amine moieties: Design, synthesis and antitubercular activity
Li, Linhu,Wang, Apeng,Wang, Bin,Liu, Mingliang,Lv, Kai,Tao, Zeyu,Ma, Chao,Ma, Xican,Han, Bing,Wang, Aoyu,Lu, Yu
, p. 409 - 412 (2020)
Seven 2,6-disubstituted N-(2-phenoxy)ethyl imidazo[1,2-a]pyridine-3-carboxamide series containing various amine moieties were designed and synthesized as new anti-TB agents. Many of them show excellent in vitro activity against both drug-sensitive MTB strain H37Rv and two MDR-MTB clinical isolates (MIC: 0.002–0.030 μg/mL). Compounds 2f, 5e and 5g display acceptable safety and pharmacokinetic profiles, opening a new direction for further development.
Substituted 2-phenyl-1,3-dioxolanes
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, (2008/06/13)
The compounds of the formula STR1 wherein one of the symbols Q and Q' is the group --CH= and the other is the group --CH= or --N=, R1, R2 and R3 each independently are hydrogen or halogen and n is the integer 0, 1 or 2, an
