55332-46-2Relevant academic research and scientific papers
Synthesis of Optically Active α-Isopropyl-4-substituted Phenylacetic Acids by Asymmetric Hydrogenation
Takemoto, Ichiki,Kawamura, Norio,Kaminaka, Hiroshi
, p. 2071 - 2072 (2007/10/02)
Homogeneous hydrogenation of 2-phenyl-3-methyl-2-butenoic acid derivatives in the presence of a catalytic amount of such chiral phosphine-rhodium complexes as Rh/(R)-BINAP, Rh/(R)-, or (S)-Cy-BINAP, Rh/(R)-p-tolyl-BINAP, and Rh/(R)-p-methoxyphenyl-BINAP afforded the corresponding phenylacetic acid derivatives in high enantiomeric excesses and in quantitative chemical yields.The optically activa phenylacetic acid derivatives are useful intermediates of agrochemicals and pharmaceuticals.
