55359-23-4

Upstream product

• 643-28-7 2-isopropylaniline 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 
• 81051-10-7 o-isopropenyl-N,N-dimethylaniline 

Downstream Products

• 1616786-27-6 2-isopropyl-N,N-dimethylaniline-N-oxide 
• 1616786-29-8 3-isopropyl-4-(N,N-dimethylamino)phenyl trifluoromethanesulfonate 
• 1616786-30-1 3-isopropyl-2-(N,N-dimethylamino)phenyl trifluoromethanesulfonate 
• 1616786-39-0 2-(N,N-dimethylamino)-3-isopropylphenyl (4-methylbenzene)sulfonate 
• 1151860-45-5 CF₃O₃S^(1-)*C₁₂H₂₀N⁽¹⁺⁾ 

Relevant academic research and scientific papers

Direct oxidative cyanation of tertiary amines promoted by in situ generated hypervalent iodine(III)-CN intermediate

An environmentally benign and metal-free cyanation method of tertiary amines oxidated by hypervalent iodine(III) intermediate generated in situ from PIFA (or DIB) and TMSCN has been developed. A variety of substituent groups on amines are tolerated to the oxidation of α-C-H bond to form C-C bond in the absence of metal catalysts with yields of up to 74%.

Metal-free functionalization of N, N-dialkylanilines via temporary oxidation to N, N-dialkylaniline N-oxides and group transfer

A simple set of protocols for the controlled elaboration of anilines is reported allowing access to a diverse array of aminophenols, aminoarylsulfonates, alkylated anilines, and aminoanilines in 29-95% yield in a single laboratory operation from easily isolable, bench-stable N,N-dialkylaniline N-oxides. The introduction of new C-O, C-C, and C-N bonds on the aromatic ring is made possible by a temporary increase in oxidation level and excision of a weak N-O bond.