55359-96-1

Usage

Uses

Used in Pharmaceutical Industry:
5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxois used as a key intermediate in the synthesis of pharmaceuticals. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxoserves as a building block in the creation of new agrochemicals. Its properties allow for the development of compounds that can be used in crop protection and other agricultural applications.
Used in Organic Synthesis:
As a building block in organic synthesis, 5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxois utilized for the production of various fine chemicals. Its versatility in chemical reactions enables the synthesis of a wide range of compounds for different applications.
Used in Research and Development:
5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxois used in research for exploring its potential medicinal and industrial applications. Its biological activities make it a subject of interest for scientists looking to innovate and discover new uses for 5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxo-.
Used in the Development of Novel Chemical Compounds:
Due to its unique structure and reactivity, 5-Thiazolecarboxaldehyde, 4-chloro-2,3-dihydro-2-oxois employed in the development of novel chemical compounds. Its properties allow for the creation of new molecules with potential applications across various industries.

InChI:InChI=1/C4H2ClNO2S/c5-3-2(1-7)9-4(8)6-3/h1H,(H,6,8)

Upstream product

• 2295-31-0 thiazoline-2,4-dione 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 127868-42-2 C₁₀H₈N₂O₂S 
• 87423-04-9 2-Oxo-8-methylthio-6-phenyl-1,2-dihydrothiazolo<3,4-a>pyrimidinium benzenesulfonate 
• 127868-41-1 C₁₆H₁₂N₂O₂S 
• 87243-13-8 C₂₁H₂₀N₄O₂S*ClH 
• 848691-22-5 5-aminothiazolo[4.5-d]pyrimidine-2,7-(3H,6H)-dione 

Relevant academic research and scientific papers

First synthesis of novel aminophenyl pyridinium-5-(hydroxybenzoyl)-hydrazonomethyl-2-oxothiazol-3-ide derivatives and evaluation of their anticancer activities

The first total synthesis for large-scale production and anticancer activity of novel aminophenylpyridinium-5-(hydroxybenzoyl)hydrazonomethyl-2-oxothiazol-3-ide (PBHT) (1) and its derivatives are reported. The chemical structure of PBHT was unambiguously

Discovery of ANA975: An oral prodrug of the TLR-7 agonist isatoribine

ANA975, a 5-amino-3-β-D-ribofuranosyl-3H-thiazolo[4,5-d]pyrimidin-2- one derivative, was synthesized in the search of an oral prodrug of isatoribine, a small molecule toll-like receptor 7 (TLR-7) agonist. Several strategies were studied to enable the kilogram-scale synthesis of ANA975. Three general total syntheses are described. In the phase I clinical study of ANA975 against hepatitis C virus (HCV), conversion to isatoribine in plasma was rapid and effective, delivering levels of isatoribine that have been shown to be clinically relevant. Copyright Taylor & Francis Group, LLC.

3-β-D-RIBOFURANOSYLTHIAZOLO[4,5-d]PYRIDIMINE NUCLEOSIDES AND USES THEREOF

The invention is directed to 3-?-D-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and pharmaceutical compositions containing such compounds that have immunomodulatory activity. The invention is also directed to the therapeutic or prophylactic use of such compounds and compositions, and to methods of treating diseases and disorders described herein, by administering effective amounts of such compounds.