55368-69-9

Usage

Uses

Used in Pharmaceutical Synthesis:
4-(2-aminoacetyl)benzonitrile hydrochloride is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the creation of diverse drug molecules, contributing to the development of novel therapeutic agents.
Used in Agrochemical Production:
In the agrochemical industry, 4-(2-aminoacetyl)benzonitrile hydrochloride is utilized as a starting material for the production of various agrochemicals. Its reactivity and functional groups enable the synthesis of compounds with pesticidal or herbicidal properties, supporting agricultural productivity and crop protection.
Used in Fine Chemicals Manufacturing:
4-(2-aminoacetyl)benzonitrile hydrochloride is employed as an intermediate in the production of fine chemicals, which are high-purity specialty chemicals used in various applications, including research, diagnostics, and high-value industrial processes. Its versatility and reactivity make it a valuable component in the synthesis of these specialized compounds.
Used in Organic Synthesis Research:
As a building block in organic synthesis, 4-(2-aminoacetyl)benzonitrile hydrochloride is used in research settings to explore new synthetic pathways and develop innovative chemical reactions. Its unique properties facilitate the investigation of novel chemical structures and the discovery of potential applications in various industries.

Upstream product

• 20099-89-2 4-Cyanophenacyl bromide 
• 622787-69-3 2-azido-1-(4'-cyanophenyl)ethanone 

Downstream Products

• 55453-05-9 2-(4-cyano-phenoxy)-N-[2-(4-cyano-phenyl)-2-oxo-ethyl]-acetamide 
• 92521-19-2 (+/-)-4-(2-amino-1-hydroxyethyl)benzonitrile 
• 92521-19-2 (S)-4-(2-amino-1-hydroxyethyl)benzonitrile 
• 92521-19-2 (R)-4-(2-amino-1-hydroxyethyl)benzonitrile 
• 349495-99-4 4-(3-tert-Butyl-1-ethyl-8-oxo-1,6,7,8-tetrahydro-pyrazolo[4,3-e][1,4]diazepin-5-yl)benzonitrile 

Relevant academic research and scientific papers

BENZIMIDAZOLE COMPOUNDS AND USE THEREOF FOR TREATING ALZHEIMER'S DISEASE OR HUNTINGTON'S DISEASE

Benzimidazole compounds of formula (I), shown below, are disclosed. The compounds are potent human glutaminyl cyclase inhibitors. Also disclosed is a pharmaceutical composition containing one of these compounds and a pharmaceutical acceptable carrier, as well as a method of treating Alzheimer's disease or Huntington's disease by administering to a subject in need thereof an effective amount of such a compound.

BENZIMIDAZOLE COMPOUNDS AND USE THEREOF FOR TREATING ALZHEIMER'S DISEASE OR HUNTINGTON'S DISEASE

Benzimidazole compounds of formula (I), shown below, are disclosed. The compounds are potent human glutaminyl cyclase inhibitors. Also disclosed is a pharmaceutical composition containing one of these compounds and a pharmaceutical acceptable carrier, as well as a method of treating Alzheimer's disease or Huntington's disease by administering to a subject in need thereof an effective amount of such a compound.

P70 S6 KINASE INHIBITORS

The present invention provides p70 S6 kinase inhibitors of the formula: pharmaceutical formulations comprising them, and methods for their use.

Asymmetric hydrogenation of α-primary and secondary amino ketones: Efficient asymmetric syntheses of (-)-arbutamine and (-)-denopamine

Two ss-receptor agonists (-)-denopamine and (-)-arbutamine were prepared in good yields and enantioselectivities by asymmetric hydrogenation of unprotected amino ketones for the first time by using Rh catalysts bearing electron-donating phosphine ligands. A series of α-primary and secondary amino ketones were synthesized and hydrogenated to produce various 1,2-amino alcohols in good yields and with good enantioselectivies. This Rh electron-donating phosphine-catalyzed asymmetric hyderogenation repI resents one of the most promising and convenient approaches towards the asymmetric synthesis of chiral amino alcohols.

ANTIBACTERIAL BENZOIC ACID DERIVATIVES

The invention provides antimicrobial agents and methods of using the agents for sterilization, sanitation, antisepsis, disinfection, and treatment of infections in mammals.

Antibacterial monic acid derivatives

A compound of the formula (I) STR1 wherein R is a group STR2 R1 is hydrogen, phenyl, C1-20 alkyl, C2-8 alkenyl or C2-8 alkynyl each of which may optionally be substituted; or C3-7 cycloalkyl, X is a divalent group --Y--C=C--, and Y is oxygen or sulphur, have antibacterial and/or antimycoplasmal activity.