55410-21-4Relevant articles and documents
BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS
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Paragraph 0408-0411, (2021/06/11)
The invention relates to certain 1,5-benzothiazepine and 1,2,5-benzothiadiazepine derivatives as defined herein. These compounds are bile acid modulators having apical sodium-dependent bile acid transporter (ASBT) and/or liver bile acid transport (LBAT) inhibitory activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment of cardiovascular diseases, fatty acid metabolism and glucose utilization disorders, gastrointestinal diseases and liver diseases.
A facile synthesis of multigram quantity of ethyl 3-ethylmorpholine-3- carboxylate
Jagodzinski, Jacek J.,Aubele, Danielle L.,Quincy, David A.,Dappen, Michael S.,Latimer, Lee H.,Hom, Roy K.,Galemmo Jr., Robert A.,Konradi, Andrei W.,Sham, Hing L.
supporting information; experimental part, p. 2471 - 2472 (2011/05/16)
A five-step synthesis of ethyl 3-ethylmorpholine-3-carboxylate proceeding from readily available 2-aminobutyric acid is detailed herein.
Hypolipidemic 1,4-benzothiazepine-1,1-dioxides
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, (2008/06/13)
The invention is concerned with novel hypolipidemic compounds of formula (I), with processes and novel intermedites for their preparation, pharmaceutical compositions containing them and with their use in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions, such as atherosclerosis. STR1