55426-75-0

Upstream product

• 883-99-8 3-hydroxy-2-naphthoic acid methyl ester 
• 92-70-6 3-Hydroxy-2-naphthoic acid 
• 100-58-3 phenylmagnesium bromide 
• 1410797-84-0 2,2-dimethyl-4H-naphtho[2,3-d][1,3]dioxin-4-one 
• 591-51-5 phenyllithium 
• 108-86-1 bromobenzene 

Downstream Products

• 86602-78-0 12-phenyl-12H-benzo[b]xanthene 
• 82379-00-8 3-(α-chloro-benzhydryl)-[2]naphthol 
• 861622-44-8 Diphenyl-(3-benzyloxy-naphthyl-⁽²⁾)-carbinol 
• 79219-99-1 naphthofuchsone 
• 309269-73-6 (Ra)-3,3'-bis[bis-(phenyl)hydroxymethyl]-2,2'-dihydroxy-1,1'-dinaphthalene 
• 309269-73-6 (S)-3,3′-bis[hydroxy(diphenyl)methyl]-1,1′-binaphthalene-2,2′-diol 
• 861332-73-2 [3-(α-chloro-benzhydryl)-[2]naphthyl]-methyl ether 
• 861355-67-1 benzyl-[3-(α-chloro-benzhydryl)-[2]naphthyl]-ether 
• 102755-12-4 (3-methoxynaphthalen-2-yl)diphenylmethanol 
• 1275596-89-8 2-phenethyl-4,4-diphenyl-4H-naphtho[2,3-d][1,3]dioxine 
• 85346-81-2 Diphenyl(3-hydroxy-2-naphthyl)methyl tert-butyl hydroperoxide 

Relevant academic research and scientific papers

Reactions of quino-ketenes with C-Nucleophiles: Syntheses of (2-Hydroxyphenyl)methanols and 2-Hydroxyphenyl Ketones

In this study, we have developed a new, efficient, and one-step protocol for the synthesis of derivatives of 2,4-dihydroxyphenyl ketones and/or 2,4-dihydroxyphenyl/naphthalenyl methanols starting from benzodioxinones/ naphthodioxinones and organolithium compounds. Reactions have been performed under thermal conditions without catalyst. This work is the first example of the preparation of these products starting from 2-hydroxy acids. Copyright

Nucleophilic addition reaction with dearomatization of naphthalene ring

Various aromatic lactones have been synthesized and their regioselectivity (1,2-addition vs. 1,4- or 1,6-addition) investigated in reactions with organolithium species, particularly n-BuLi and sec-BuLi. The regioselectivity varied greatly depending on various factors, such as the bulkiness of both substrates and organolithium species, and types of solvent and cosolvent. In particular, 1,4-addition with dearomatization occurred preferentially using sec-BuLi as the nucleophile in tetrahydrofuran (THF) with hexamethylphosphoramide (HMPA) or N,N′-dimethylpropyleneurea (DMPU) as cosolvent. For sec-BuLi, the reaction was estimated to proceed through a single-electron transfer mechanism.

NaHSO4/SiO2catalyzed generation of: o -quinone/ o -thioquinone methides: synthesis of arylxanthenes/ arylthioxanthenes via oxa-6π-electrocyclization

ortho-Quinone methides, very reactive transient intermediates, are utilized successfully in synthesizing complex organic molecules of natural and biological significance. Among several synthetic protocols, the acid catalyzed generation of ortho-quinone me

Desymmetrization of Symmetrical Triarylcarbinols: Synthesis of 7-Arylfluorenes and a C 2 -Symmetric Chiral BIFOL Phosphoric Acid

A simple and an efficient method for the synthesis of 7-arylfluorenes by intramolecular cyclization of the corresponding triarylcarbinols in the presence of the solid-acid catalyst NaHSO 4 /SiO 2 has been developed. By using this method, a new chiral diol with a C 2 -symmetric bisfluorenyl unit, 7,7′-diphenyl-7 H,7′ H -5,5′-bibenzo[ c ]fluorene-6,6′-diol (BIFOL), having central chirality was synthesized in an optically active form from (S)-(-)-BINOL-3,3′-dicarboxylic acid. The absolute configuration of the chiral bisfluorene derivative BIFOL was ascertained by single-crystal X-ray analysis. Furthermore, a new chiral phosphoric acid was synthesized from BIFOL and evaluated for enantioselective transfer hydrogenation.