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1-(1,3-benzodioxol-5-ylmethyl)-4-[(2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl]piperazine, commonly known as Tadalafil, is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction and pulmonary arterial hypertension. It functions by relaxing muscles and enhancing blood flow to specific areas of the body, providing relief from the symptoms of these conditions.

55436-48-1

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55436-48-1 Usage

Uses

Used in Pharmaceutical Industry:
Tadalafil is used as a medication for treating erectile dysfunction and pulmonary arterial hypertension. It works by increasing blood flow to the penis, aiding in achieving and maintaining an erection, and by relaxing the blood vessels in the lungs, improving the ability to exercise in patients with pulmonary arterial hypertension.
Used in Research and Development:
Tadalafil is also utilized in the research and development of new treatments for various cardiovascular and pulmonary conditions, as well as potential applications in other therapeutic areas due to its mechanism of action as a PDE5 inhibitor.

Check Digit Verification of cas no

The CAS Registry Mumber 55436-48-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,4,3 and 6 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 55436-48:
(7*5)+(6*5)+(5*4)+(4*3)+(3*6)+(2*4)+(1*8)=131
131 % 10 = 1
So 55436-48-1 is a valid CAS Registry Number.

55436-48-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(1,3-benzodioxol-5-ylmethyl)-4-[(E)-3,7,11,15-tetramethylhexadec-2-enyl]piperazine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:55436-48-1 SDS

55436-48-1Upstream product

55436-48-1Downstream Products

55436-48-1Relevant academic research and scientific papers

Non anticholinergic gastric acid secretion inhibitors. New piperazine and related derivatives

Tricerri,Elitropi,Panto,et al.

, p. 555 - 562 (2007/10/08)

Some of the new piperazine derived compounds exhibited interesting gastric antisecretory properties without anticholinergic action. 1 Piperonyl 4 (3,7,11 trimethyl 2,6,10 dodecatrienyl) piperazine was the most active as an antisecretory agent in rat. Some analogous compounds, with the piperazine ring replaced by other heterocyclic or acyclic amines, were also prepared. Structure activity relationships are discussed.

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