554411-20-0

Basic information

• Product Name: 4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER
• Synonyms: 4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER;2-(4-Methoxy-3-nitrophenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane
• CAS NO: 554411-20-0
• Molecular Formula: C₁₃H₁₈BNO₅
• Molecular Weight: 279.1
• Mol File: 554411-20-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 393.7 °C at 760 mmHg
• Flash Point: 191.9 °C
• Appearance: /
• Density: 1.16 g/cm³
• Vapor Pressure: 4.75E-06mmHg at 25°C
• Refractive Index: 1.513
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER(554411-20-0)
• EPA Substance Registry System: 4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER(554411-20-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 554411-20-0(Hazardous Substances Data)

Usage

General Description

4-Methoxy-3-nitrophenylboronic acid, pinacol ester is a chemical compound that is commonly used in organic synthesis. It is a boronic acid ester, which means it contains a boron atom bonded to a phenyl ring, a methoxy group, and a nitro group. The pinacol ester portion refers to the presence of a pinacol group, which is a type of organic functional group that contains two tertiary butyl groups bonded to a central carbon atom. 4-Methoxy-3-nitrophenylboronic acid, pinacol ester is often used as a reagent in Suzuki-Miyaura cross-coupling reactions, which are important in the field of organic chemistry for forming carbon-carbon bonds. 4-Methoxy-3-nitrophenylboronic acid, pinacol ester is a valuable tool for chemists in the synthesis of complex organic molecules.

InChI:InChI=1/C13H18BNO5/c1-12(2)13(3,4)20-14(19-12)9-6-7-11(18-5)10(8-9)15(16)17/h6-8H,1-5H3

Upstream product

• 33696-00-3 4-bromo-1-methoxy-2-nitrobenzene 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 554411-21-1 4-(4-methoxy-3-nitro-phenyl)-3,6-dihydro-2H-pyran 

Relevant articles and documents

ARYL AND HETEROARYL COMPOUNDS, AND THERAPEUTIC USES THEREOF IN CONDITIONS ASSOCIATED WITH THE ALTERATION OF THE ACTIVITY OF GALACTOCEREBROSIDASE

The application is directed to compounds of formulae (IA) and (IB): (IA) and (IB), and their salts and solvates, wherein R1a, R2a, A1, A2, A3, A4, R1b, R2b, B1, B2, B3, and G are as set forth in the specification, as well as to methods for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or prevention of, e.g., lysosomal storage diseases, such as Krabbe's disease, and α-synucleinopathies, such as Parkinson's disease.

TOLL-LIKE RECEPTOR 8 (TLR8)-SPECIFIC ANTAGONISTS AND METHODS OF MAKING AND USES THEREOF

Toll-like receptor 8 (TLR8)-specific inhibitors and methods of using the same in individuals having an autoimmune disease or an inflammatory disorder.

Benzothiazole derivatives

This invention relates to compounds of formula I wherein R1 and R2 are defined herein, or a pharmaceutically acceptable salt thereof. It has been found that the compounds of formula I are adenosine receptor ligands with good affinity to the A2A-receptor and a high selectivity to the A1- and A3 receptors. These compounds are useful, inter alia, in treatment of Alzheimer's disease, depression, Parkinson's disease and ADHD.