554411-20-0

Basic information

• Product Name: 4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER
• Synonyms: 4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER;2-(4-Methoxy-3-nitrophenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane
• CAS NO: 554411-20-0
• Molecular Formula: C₁₃H₁₈BNO₅
• Molecular Weight: 279.1
• Mol File: 554411-20-0.mol

Chemical Properties

• Boiling Point: 393.7 °C at 760 mmHg
• Flash Point: 191.9 °C
• Appearance: /
• Density: 1.16 g/cm³
• Vapor Pressure: 4.75E-06mmHg at 25°C
• Refractive Index: 1.513
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER(554411-20-0)
• EPA Substance Registry System: 4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER(554411-20-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 554411-20-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
4-Methoxy-3-nitrophenylboronic acid, pinacol ester is used as a reagent for Suzuki-Miyaura cross-coupling reactions, which are pivotal in organic chemistry for creating carbon-carbon bonds. This application is crucial for the formation of various complex organic molecules, making it an indispensable tool for chemists in the field.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Methoxy-3-nitrophenylboronic acid, pinacol ester is employed as a key intermediate in the synthesis of pharmaceutical compounds. Its unique structure allows for the creation of diverse molecular frameworks, contributing to the development of new drugs with potential therapeutic applications.
Used in Material Science:
4-Methoxy-3-nitrophenylboronic acid, pinacol ester is utilized in material science for the synthesis of advanced materials with specific properties. Its ability to form carbon-carbon bonds through Suzuki-Miyaura cross-coupling reactions enables the creation of materials with tailored characteristics for various applications, such as electronics, sensors, and energy storage devices.
Used in Research and Development:
In research and development, 4-Methoxy-3-nitrophenylboronic acid, pinacol ester is employed as a valuable tool for exploring new chemical reactions and mechanisms. Its unique structure and reactivity provide insights into the fundamental aspects of organic chemistry, paving the way for the discovery of novel synthetic methods and applications.

InChI:InChI=1/C13H18BNO5/c1-12(2)13(3,4)20-14(19-12)9-6-7-11(18-5)10(8-9)15(16)17/h6-8H,1-5H3

Upstream product

• 33696-00-3 4-bromo-1-methoxy-2-nitrobenzene 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 554411-21-1 4-(4-methoxy-3-nitro-phenyl)-3,6-dihydro-2H-pyran 

Relevant articles and documents

Polycyclic compound, polymer, mixture, composition, and organic electronic device

The invention relates to a polycyclic compound, a polymer containing the same, a mixture, a composition and an organic electronic device. The polycyclic compound provided by the invention contains a plurality of different ring systems which are connected

ARYL AND HETEROARYL COMPOUNDS, AND THERAPEUTIC USES THEREOF IN CONDITIONS ASSOCIATED WITH THE ALTERATION OF THE ACTIVITY OF GALACTOCEREBROSIDASE

The application is directed to compounds of formulae (IA) and (IB): (IA) and (IB), and their salts and solvates, wherein R1a, R2a, A1, A2, A3, A4, R1b, R2b, B1, B2, B3, and G are as set forth in the specification, as well as to methods for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or prevention of, e.g., lysosomal storage diseases, such as Krabbe's disease, and α-synucleinopathies, such as Parkinson's disease.

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Toll-like receptor 8 (TLR8)-specific inhibitors and methods of using the same in individuals having an autoimmune disease or an inflammatory disorder.

Carbamic acid esters of benzothiazoles

The present invention relates to a compound of formula I wherein R, X and n are defined hereinabove, and to a pharmaceutically acceptable salt thereof. The compound may be used for the treatment of diseases related to the A2A receptor.

Benzothiazole derivatives

This invention relates to compounds of formula I wherein R1 and R2 are defined herein, or a pharmaceutically acceptable salt thereof. It has been found that the compounds of formula I are adenosine receptor ligands with good affinity to the A2A-receptor and a high selectivity to the A1- and A3 receptors. These compounds are useful, inter alia, in treatment of Alzheimer's disease, depression, Parkinson's disease and ADHD.

Benzothiazoles

The present invention relates to compounds of the formula wherein R1 and R2 are as described within. The compounds of formula I have been found to be adenosine receptor ligands. Specifically, the compounds of the present invention have a good affinity to the A2A-receptor and they may be used in the treatment of diseases, related to this receptor.