554412-88-3

Upstream product

• 530-62-1 1,1'-carbonyldiimidazole 
• 554412-82-7 2-(2-amino-ethylamino)-5-(benzyloxycarbonyl-methyl-amino)-4-oxo-5,6-dihydro-4H-pyrimidine-1-carboxylic acid tert-butyl ester 
• 554412-68-9 5-(benzyloxycarbonyl-methyl-amino)-2-methylsulfanyl-4-oxo-5,6-dihydro-4H-pyrimidine-1-carboxylic acid tert-butyl ester 
• 554412-64-5 methyl-(2-methylsulfanyl-4-oxo-1,4,5,6-tetrahydro-pyrimidin-5-yl)-carbamic acid benzyl ester 
• 56776-33-1 2-(Benzyloxycarbonyl-methyl-amino)-acrylic acid methyl ester 

Relevant academic research and scientific papers

A new and convergent synthesis for 2,5-diamino-tetrahydropyrimidones

AN1057A/B has shown potent activity against MRSA. A novel and concise route to the synthesis of its heterocycle core 2,5-diamino-5,6-dihydro-1H-pyrimidine-4-one is described. This methodology allows the synthesis of an array of analogs with different amin