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55443-56-6

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55443-56-6 Usage

Description

(13)C5H7NO3, also known as L-Pyroglutamic Acid-13C5, is an isotope-labeled analog of L-Pyroglutamic Acid (P997480), a naturally occurring amino acid. (13)C5H7NO3 is characterized by the presence of the stable isotope carbon-13 (13C) in its molecular structure, which distinguishes it from the naturally occurring form. L-Pyroglutamic Acid is involved in the synthesis of peptides and has been observed to convert when placed at the N-terminus in vivo to create IgG2 antibodies.

Uses

Used in Pharmaceutical and Biomedical Research:
(13)C5H7NO3 is used as a research tool in pharmaceutical and biomedical applications for its unique properties as an isotope-labeled compound. The incorporation of 13C allows for the tracking and analysis of metabolic pathways and biochemical processes in living organisms, providing valuable insights into the mechanisms of drug action and metabolism.
Used in Peptide Synthesis:
In the field of peptide synthesis, (13)C5H7NO3 serves as a key building block for the creation of novel peptides with specific properties. The isotope labeling can enhance the stability and activity of the synthesized peptides, making them more suitable for therapeutic applications.
Used in Immunology and Antibody Production:
(13C5H7NO3 is utilized in immunology for the production of IgG2 antibodies. Its conversion at the N-terminus in vivo contributes to the development of antibodies with improved characteristics, such as increased affinity and specificity, which can be crucial for diagnostic and therapeutic purposes.
Used in Drug Development and Metabolism Studies:
(13C5H7NO3 is employed in drug development to study the metabolism and pharmacokinetics of new drug candidates. The isotope labeling enables researchers to monitor the fate of the compound within the body, providing valuable data on absorption, distribution, metabolism, and excretion, which are essential for optimizing drug design and safety assessment.

Check Digit Verification of cas no

The CAS Registry Mumber 55443-56-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,4,4 and 3 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 55443-56:
(7*5)+(6*5)+(5*4)+(4*4)+(3*3)+(2*5)+(1*6)=126
126 % 10 = 6
So 55443-56-6 is a valid CAS Registry Number.

55443-56-6Upstream product

55443-56-6Downstream Products

55443-56-6Relevant articles and documents

N-(2-aminoethyl)glycine and amino acids from interstellar ice analogues

Meinert, Cornelia,Filippi, Jean-Jacques,De Marcellus, Pierre,Le Sergeant D'Hendecourt, Louis,Meierhenrich, Uwe J.

, p. 186 - 191 (2013/01/13)

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