55443-60-2 Usage
Description
L-TYROSINE-13C9 is a stable isotope-labeled compound of L-Tryptophan, an essential amino acid. The incorporation of carbon-13 (13C) into the tyrosine molecule allows for enhanced detection and tracking of metabolic processes and pathways involving this amino acid. This labeled compound is particularly useful in research and diagnostic applications where the differentiation between endogenous and exogenous sources of L-Tryptophan is necessary.
Uses
Used in Research Applications:
L-TYROSINE-13C9 is used as a research tool for studying the metabolism and physiological roles of L-Tryptophan in various biological systems. The stable isotope labeling facilitates the tracing of metabolic pathways and the investigation of enzyme activities and interactions involving this amino acid.
Used in Diagnostic Applications:
In the field of diagnostics, L-TYROSINE-13C9 serves as a valuable compound for the assessment of amino acid metabolism disorders. The stable isotope labeling allows for the accurate measurement of L-Tryptophan levels and its metabolic products, aiding in the diagnosis and monitoring of related conditions.
Used in Pharmaceutical Development:
L-TYROSINE-13C9 is utilized in the development of pharmaceuticals targeting L-Tryptophan metabolism. The stable isotope-labeled compound can be employed to evaluate the efficacy of drugs and their impact on metabolic pathways, contributing to the advancement of therapeutic strategies for various diseases.
Used in Nutritional Studies:
In nutritional research, L-TYROSINE-13C9 is used to investigate the role of L-Tryptophan in dietary intake and its contribution to overall health and well-being. The stable isotope labeling enables the tracking of L-Tryptophan absorption, utilization, and metabolism in the body, providing insights into optimal dietary requirements and supplementation strategies.
Used in Metabolic Disease Research:
L-TYROSINE-13C9 is employed in the study of metabolic diseases related to L-Tryptophan metabolism. The stable isotope-labeled compound helps researchers to better understand the underlying mechanisms and pathophysiology of these conditions, potentially leading to the development of novel therapeutic approaches and interventions.
Check Digit Verification of cas no
The CAS Registry Mumber 55443-60-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,4,4 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 55443-60:
(7*5)+(6*5)+(5*4)+(4*4)+(3*3)+(2*6)+(1*0)=122
122 % 10 = 2
So 55443-60-2 is a valid CAS Registry Number.
55443-60-2Relevant articles and documents
STABLE ISOTOPE-LABELED AMINO ACID, METHOD OF INTEGRATING THE SAME INTO TARGET PROTEIN, METHOD OF NMR STRUCTURAL ANALYSIS OF PROTEIN AND PROCESS FOR PRODUCING SITE-SELECTIVE STABLE ISOTOPE-LABELED FUMARIC ACID AND TARTARIC ACID
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Page 22, (2010/02/08)
The present invention provides a stable isotope-labeled amino acid which is at least one of amino acids constituting a protein and which has at least one of the following labeling patterns:(a) hydrogen atoms except at least one hydrogen atom in one or more methylene groups are deuterated,(b) hydrogen atoms in one of prochiral gem-methyl groups are completely deuterated,(c) hydrogen atoms in prochiral methyl groups are partially deuterated, and(d) all hydrogen atoms except one of them in methyl group are deuterated and hydrogen atoms in the aromatic ring are partially deuterated. With the stable isotope-labeled amino acid, the deuteration of protein can be attained without damaging the NMR sensitivity of remaining hydrogen nucleus and, in addition, the rapid, accurate analysis of NMR spectrum of a high-molecular protein which is beyond the limitation in the prior art and the determination of the stereo-structure can be performed at the same time.
