554430-14-7Relevant articles and documents
Novel chromene-derived selective estrogen receptor modulators useful for alleviating hot flushes and vaginal dryness
Jain, Nareshkumar,Kanojia, Ramesh M.,Xu, Jiayi,Jian-Zhong, Guo,Pacia, Emmanuel,Lai, Muh-Tsann,Du, Fuyong,Musto, Amy,Allan, George,Hahn, DoWon,Lundeen, Scott,Sui, Zhihua
, p. 3056 - 3059 (2007/10/03)
A novel SERM (selective estrogen receptor modulators), 1-(R), a chromene-derived bisbenzopyran, was discovered to alleviate hot flushes and effectively increase vaginal fluidity in rats. Moreover, 1-(R) was found to have beneficial effects on plasma chole