554453-80-4Relevant academic research and scientific papers
Synthesis and biological activities of novel β-carbolines as PDE5 inhibitors
Sui, Zhihua,Guan, Jihua,Macielag, Mark J.,Jiang, Weiqin,Qiu, Yuhong,Kraft, Patricia,Bhattacharjee, Sheela,John, T. Matthew,Craig, Elizabeth,Haynes-Johnson, Donna,Clancy, Joanna
, p. 761 - 765 (2003)
A series of N2-furoyl and N2pyrimidinyl β-carbolines was discovered to possess potent inhibitory activity against PDE5. During the synthesis we developed a tandem resin quenching protocol, which allowed us to synthesize large number
