55457-17-5

Usage

Uses

Used in Pharmaceutical Industry:
Pyrazolo[1,5-a]-1,3,5-triazin-4(1H)-one, 2-methyl(9CI) is used as an intermediate in the synthesis of various pharmaceutical compounds for its anti-tumor, anti-inflammatory, and antimicrobial properties. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical field, Pyrazolo[1,5-a]-1,3,5-triazin-4(1H)-one, 2-methyl(9CI) serves as a key intermediate in the creation of agrochemicals that possess biological activities beneficial for crop protection and enhancement of agricultural productivity.
Used in Organic Synthesis and Medicinal Chemistry Research:
Pyrazolo[1,5-a]-1,3,5-triazin-4(1H)-one, 2-methyl(9CI) is also utilized as an important intermediate in organic synthesis and medicinal chemistry research, where its unique structure allows for the development of novel chemical entities with potential applications in various fields.

Upstream product

• 51043-62-0 N-(pyrazol-3-yl)acetamidine acetate 
• 105-58-8 Diethyl carbonate 
• 51247-95-1 N-(1H-pyrazol-5-yl)acetamidine 

Downstream Products

• 476468-38-9 2-methyl-4-(N-methyl-N-phenylamino)pyrazolo[1,5-a]-1,3,5-triazin-4-one 
• 476468-49-2 8-(2'-deoxy-β-D-ribofuranosyl)-2-methyl-4-(N-methylamino)pyrazolo[1,5-a]-1,3,5-triazine 3',5'-bis(dibenzyl phosphate) 
• 476468-52-7 8-(2'-deoxy-β-D-xylofuranosyl)-2-methyl-4-(N-methylamino)pyrazolo[1,5-a]-1,3,5-triazine 3',5'-cyclic phosphate benzyl ester 
• 476468-46-9 2-methyl-4-(N-methyl-N-phenylamino)-8-(β-D-glycero-pentofuran-3'-ulose-1'-yl)pyrazolo[1,5-a]-1,3,5-triazine 
• 476468-50-5 8-(2'-deoxy-β-D-xylofuranosyl)-2-methyl-4-(N-methyl-N-phenylamino)pyrazolo[1,5-a]-1,3,5-triazine 
• 476468-47-0 8-(2'-deoxy-β-D-ribofuranosyl)-2-methyl-4-(N-methyl-N-phenylamino)pyrazolo[1,5-a]-1,3,5-triazine 
• 476468-45-8 8-iodo-2-methyl-4-(N-methyl-N-phenylamino)pyrazolo[1,5-a]-1,3,5-triazin-4-one 
• 515880-20-3 [2-methyl-4-(methyl-phenyl-amino)-pyrazolo[1,5-a][1,3,5]triazin-8-yl]-(3-trifluoromethyl-phenyl)-methanone 
• 515880-19-0 (4-methoxy-phenyl)-[2-methyl-4-(methyl-phenyl-amino)-pyrazolo[1,5-a][1,3,5]triazin-8-yl]-methanone 
• 515880-21-4 (2-chloro-phenyl)-[2-methyl-4-(methyl-phenyl-amino)-pyrazolo[1,5-a][1,3,5]triazin-8-yl]-methanone 
• 515880-11-2 8-benzoyl-2-methyl-4-(N-methyl-N-phenylamino)pyrazolo[1,5-a]-1,3,5-triazine 
• 515880-23-6 2-methyl-4-(methyl-phenyl-amino)-pyrazolo[1,5-a][1,3,5]triazine-8-carboxylic acid diethylamide 
• 515880-22-5 ethyl 2-methyl-4-(N-methyl-N-phenylamino)pyrazolo-[1,5-a]-1,3,5-triazine-8-carboxylate 

Relevant academic research and scientific papers

N-ARYL-ISOXAZOLOPYRIMIDIN-4-AMINES AND RELATED COMPOUNDS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF

Disclosed are N-aryl-isoxazolopyrimidin-4-amines and related compounds thereof, represented by the Formula (I): wherein Ar, R1-R5, A, B, D, E, F and H are defined herein. The present invention relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.

Novel substituted pyrazolo[1,5 a]-1,3,5-triazine derivatives and their analogues, pharmaceutical compositions containing same, use thereof as medicine and methods for preparing same

The invention concerns novel substituted pyrazolo[1,5 A]-1,3,5-triazine derivatives and some of their structural analogues, and their therapeutic uses, more particularly for preventing and treating pathologies involving central and/or peripheral neuronal degeneration. The invention also concerns methods for preparing same and novel synthesis intermediates. The compounds of the invention correspond more particularly to general formulae (Ia) and (Ib).