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3-(p-chlorophenyl)-3-(2-pyridyl)propanal is an organic compound with the molecular formula C15H12ClNO. It is a derivative of propanal, featuring a p-chlorophenyl group (a phenyl ring with a chlorine atom attached to the para position) and a 2-pyridyl group (a pyridine ring with the nitrogen atom at the 2nd position) attached to the third carbon of the propanal backbone. 3-(p-chlorophenyl)-3-(2-pyridyl)propanal is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, particularly as an intermediate in the production of certain drugs. Its chemical structure and properties make it a valuable component in the development of new molecules with specific therapeutic or pesticidal effects.

55486-47-0

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55486-47-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 55486-47-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,4,8 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 55486-47:
(7*5)+(6*5)+(5*4)+(4*8)+(3*6)+(2*4)+(1*7)=150
150 % 10 = 0
So 55486-47-0 is a valid CAS Registry Number.

55486-47-0Downstream Products

55486-47-0Relevant academic research and scientific papers

New synthetic route to N,N-disubstituted 3-aryl-3-pyridylpropylamines: Pheniramines from 3-aryl-3-(2-pyridyl)propanals

Marchetti, Mauro,Sechi, Barbara,Azzena, Ugo,Botteghi, Carlo,Paganelli, Stefano,Ponte, Gino Del,Stefani, Helio A.

, p. 219 - 225 (2007/10/03)

3-Aryl-3-(2-pyridyl)propanals 3, useful precursors compound for the H1 antihistaminic agents Pheniramines 1 were prepared following three different reaction pathways: the first one involves the rhodium catalyzed regiospecific hydroformylation of cinnamaldehyde acetals 4; the second one was carried out through the hydro-hydroxyacetamidation reaction on 1-aryl-1-(2-pyridyl)ethenes 2 followed by oxidative cleavage of the intermediate α-hydroxybutanamides 10; the third one was accomplished through alkylation of 2-benzylpyridines 12 with 2-bromomethyl-1,3-dioxolane 13 using LDA as deprotonating agent. The last preparative route showed to be the most convenient giving Pheniramine 1 up to 80 percent overall yield.

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