55489-32-2

Usage

InChI:InChI=1/C17H18N2OS/c1-3-19(4-2)12-9-10-13(15(20)11-12)17-18-14-7-5-6-8-16(14)21-17/h5-11,18H,3-4H2,1-2H3/b17-13-

Upstream product

• 23050-90-0 4-(diethylamino)-2-hydroxybenzoic acid 
• 137-07-5 2-amino-benzenethiol 
• 149977-31-1 4-(benzo[d]thiazol-2-yl)-N,N-diethyl-3-methoxybenzenamine 
• 65-49-6 4-Aminosalicylic acid 
• 88877-62-7 2-(2’-hydroxy-4’-aminophenyl)benzothiazole 
• 91-68-9 3-diethylaminophenol 
• 17754-90-4 4-(Diethylamino)salicylaldehyde 

Relevant academic research and scientific papers

AIE-based fluorescent boronate probe and its application in peroxynitrite imaging

Fluorescent probes have contributed greatly to our understanding of the biological role of peroxynitrite (ONOO–). The ONOO– fluorescence probe characterized by the arlyboronate received a moderate opening fluorescence response, and t

A novel carbonothioate-based benzothiazole fluorescent probe for trace detection of mercury (II) in real water samples

In this study, a novel turn-on Hg2+ fluorescent probe (2-(1,3-benzothiazol-2-yl)-5-(N,N-diethylamino) phenol)-phenyl carbonothioate (PT) was designed and synthesized. The structure of fluorescent probe PT was characterized by spectral data and

Small bifunctional chelators that do not disaggregate amyloid β fibrils exhibit reduced cellular toxicity

Multifunctional metal chelators that can modulate the amyloid β (Aβ) peptide aggregation and its interaction with metal ions such as copper and zinc hold considerable promise as therapeutic agents for Alzheimers disease (AD). However, specific rather than

Highly selective turn-on fluorogenic chemosensor for Zn2+ based on chelation enhanced fluorescence

A new fluorescent zinc sensor was constructed based on cyclic and noncyclic Schiff's bases obtained by the condensation of 4?(diethylamino) salicylaldehyde and 2?aminobenzenethio under two different catalytic conditions such as sulphuric acid yields 2?(be

A novel acidic pH fluorescent probe based on a benzothiazole derivative

A novel acidic pH fluorescent probe 1 based on a benzothiazole derivative has been designed, synthesized and developed. The linear response range covers the acidic pH range from 3.44 to 6.46, which is valuable for pH researches in acidic environment. The evaluated pKa value of the probe 1 is 4.23. The fluorescence enhancement of the studied probe 1 with an increase in hydrogen ions concentration is based on the hindering of enhanced photo-induced electron transfer (PET) process. Moreover, the pH sensor possesses a highly selective response to H+ in the presence of metal ions, anions and other bioactive small molecules which would be interfere with its fluorescent pH response. Furthermore, the probe 1 responds to acidic pH with short response time that was less than 1 min. The probe 1 has been successfully applied to confocal fluorescence imaging in live HeLa cells and can selectively stain lysosomes. All of such good properties prove it can be used to monitoring pH fluctuations in acidic environment with high sensitivity, pH dependence and short response time.

An ESIPT based versatile fluorescent probe for bioimaging live-cells andE. coliunder strongly acidic conditions

A 2-(2-hydroxyphenyl)benzothiazole based probeBTNNundergoes a drastic upsurge (～146-fold,Φ= 69%) in fluorescence intensity (bright green,λem530 nm) on going from pH 7 to 2. MG-63 cells andE. colibacteria internalizeBTNNwithout toxicity and its

A selective fluorescent sensor for cysteine detection with potential as a white light emitting fluorophore in living cell imaging

A novel fluorescent sensor CysW-1 was introduced for cysteine detection via the cleavage reaction of two fluorophores. It exhibited advantages including high sensitivity, high selectivity and low toxicity. By optimizing the conditions, a relatively steady

Highly efficient AgNO3-catalyzed approach to 2-(benzo[d]azol-2-yl)phenols from salicylaldehydes with 2-aminothiophenol, 2-aminophenol and benzene-1,2-diamine

A new, convenient and efficient AgNO3-catalyzed strategy for the preparation of 2-(benzo[d]azol-2-yl)phenol derivatives in good to excellent yields (63–98%) is described. The reaction proceeds via condensation/intramolecular nucleophilic addition/oxidation process between substituted salicylaldehydes and 2-aminothiophenol, 2-aminophenol or benzene-1,2-diamine under mild reaction conditions. Notably, this reaction utilizes cheap AgNO3 as a readily available and low-cost benign oxidant at low catalyst loadings with excellent functional group tolerance.

New organoboron compounds and the use thereof

PURPOSE: An organoboron compound with a blue light emitting property is provided to manufacture and realize an organic light emitting diode(OLED). CONSTITUTION: An organoboron compound or a salt thereof is denoted by chemical formula 1. The compound emits

Yttrium-catalyzed heterocyclic formation via aerobic oxygenation: A green approach to benzothiazoles

The YCl3-catalyzed aerobic oxidative cyclization reaction for the synthesis of benzothiazoles has been developed. This method provides a practical, effective and green synthetic approach to benzothiazoles which are important units in many biologically active compounds.