55504-16-0Relevant academic research and scientific papers
Cyclization of N,N-diethylgeranylamine N-oxide in one-pot operation: preparation of cyclic terpenoid-aroma chemicals
Takabe, Kunihiko,Yamada, Takashi,Miyamoto, Takenori,Mase, Nobuyuki
scheme or table, p. 6016 - 6018 (2009/04/11)
Acid promoted cyclization of the geranylamine N-oxide (E)-4 followed by base-catalyzed intramolecular aldol condensation afforded 1-acetyl-4,4-dimethyl-1-cyclohexene (7) in one-pot operation. Reduction of 7, which possess strong fruity odor, followed by lipase-catalyzed kinetic resolution furnished the acetate (R)-26 (>49.9% yield, >99% ee) and the recovered alcohol (S)-25 (>49.9% yield, >99% ee, herbal odor).
Friedel-Crafts Reactions of Some Vinyisilanes
Fleming, Ian,Pearce, Andrew
, p. 2485 - 2489 (2007/10/02)
Substituted cyclohexenylsilanes (2), (5), (9), and (13) undergo Friedel-Crafts reactions to give substitution products, site-selectively at the carbon atom carrying the trimethylsilyl group. β-Trimethylsilylstyrene (17) similary gives more substitution in Friedel-Crafts reactions with benzoyl chloride and with phenylacetyl chloride than styrene itself.The syntheses of the silanes are reported, and some limitations of the idea identified.
