555153-61-2Relevant academic research and scientific papers
PIPERIDINYLHYDROXYETHYLPIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTORS
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Page/Page column 28-29, (2009/05/28)
The present invention relates to a compound of the formula (I), or a pharmaceutically acceptable salt thereof, wherein R1-R8 and X, m, and n are defined. Compounds and compositions of the present invention are useful the treatment of atherosclerosis.
Diastereoselective conjugate addition of organocuprates to chiral racemic olefinic amido esters. Formal total synthesis of paroxetine
Cossy, Janine,Mirguet, Olivier,Gomez Pardo, Domingo,Desmurs, Jean-Roger
, p. 475 - 482 (2007/10/03)
The diastereoselective conjugate addition of an organocopper reagent to a chiral racemic olefinic amido ester has been used as the key step in a formal total synthesis of paroxetine.
Synthesis of 3-Aminolactams as X-Gly Constrained Pseudodipeptides and Conformational Study of a Trp-Gly Surrogate
Ecija, Marta,Diez, Anna,Rubiralta, Mario,Casamitjana, Nuria,Kogan, Marcelo J.,Giralt, Ernest
, p. 9541 - 9553 (2007/10/03)
3-Amino-δ-valerolactams trans-11a-c were synthesized through conjugate addition and Curtius rearrangement and converted into Fmoc-{Trp-Gly}, Fmoc-{Ile-Gly}, and Fmoc-{Phe-Gly} pseudodipeptides. Conformational analyses of tripeptide analogues Ac-{Trp-Gly}-
