555154-79-5Relevant academic research and scientific papers
Highly selective synthesis of (E)-3-methyl-1-trialkylsilyl-3-en-1-ynes via trans-selective alkynylation catalyzed by Cl2Pd(DPEphos) and stereospecific methylation with methylzincs catalyzed by Pd(tBu3P)2.
Shi, Ji-Cheng,Zeng, Xingzhong,Negishi, Ei-Ichi
, p. 1825 - 1828 (2003)
[reaction: see text] trans-Selective (>or=98%) monoalkynylation of 1,1-dibromo-1-alkenes and 1,1-dichloro-1-alkenes catalyzed by Cl(2)Pd(DPEphos) followed by stereospecific methylation with Me(2)Zn or MeZnX (X= Cl or Br) catalyzed by Pd((t)()Bu(3)P)(2) pr
Palladium-catalyzed trans-selective alkynylation-alkylation tandem process for the synthesis of (E)-3-alkyl-1-trialkylsilyl-3-alken-1-ynes
Negishi, Ei-Ichi,Shi, Ji-Cheng,Zeng, Xingzhong
, p. 9886 - 9895 (2007/10/03)
The Pd-catalyzed trans-selective monoalkynylation of 1,1-dihalo-1-alkenes with XZnCCSiMe3, where X is Br or Cl, can proceed generally in excellent yields in the presence of Pd(DPEphos)Cl2 or Pd(dppf)Cl 2, and subsequent al
