555154-94-4Relevant academic research and scientific papers
PURINE DERIVATIVES AS KINASE INHIBITORS
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Page/Page column 47, (2008/06/13)
The present invention provides kinase inhibitors of Formula I.
KINASE INHIBITORS
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Page/Page column 31, (2010/02/07)
The present invention provides kinase inhibitors of Formula (I)
An improved method for direct conversion of heteroaryl-aldehydes to heteroaryl-acetonitriles
Engler, Thomas A.,Furness, Kelly,Malhotra, Sushant,Diefenbacher, Clive,Clayton, Joshua R.
, p. 2903 - 2905 (2007/10/03)
Treatment of heteroaryl-aldehydes with diethyl cyanophosphonate in the presence of a catalytic amount of LiCN affords phosphorylated cyanohydrins which are reduced in situ with SmI2 to give heteroaryl-acetonitriles in generally good overall yields (50-100%). The generality of the process is demonstrated.
