55526-63-1

Basic information

• Product Name: 2-CHLOROMALONDIANIL HYDROCHLORIDE
• Synonyms: 2-CHLOROMALONDIANIL HYDROCHLORIDE
• CAS NO: 55526-63-1
• Molecular Formula: C15H14Cl2N2
• Molecular Weight: 293.19
• Mol File: 55526-63-1.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-CHLOROMALONDIANIL HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROMALONDIANIL HYDROCHLORIDE(55526-63-1)
• EPA Substance Registry System: 2-CHLOROMALONDIANIL HYDROCHLORIDE(55526-63-1)

Safety Data

• Hazardous Substances Data: 55526-63-1(Hazardous Substances Data)

Upstream product

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• 766-40-5 Mucochloric acid 
• 142-04-1 aniline hydrochloride 
• 87-56-9 mucochloric acid 

Relevant articles and documents

Single photon DNA photocleavage at 830 nm by quinoline dicarbocyanine dyes

We have synthesized symmetrical carbocyanine dyes in which two 4-quinolinium rings are joined by a pentamethine bridge that is meso-substituted with H or Cl. Irradiation of the halogenated dye at 830 nm produces hydroxyl radicals that generate DNA direct

COMPOUNDS FOR PHOTODYNAMIC THERAPY AND RELATED USES

Disclosed herein are symmetrical and unsymmetrical carbocyanine dyes. Irradiation of the dyes generates reactive species which contribute to DNA damage. The dyes are useful for the treatment of various cancers and cell growth disorders.

Polymethine Thiopyrylium Fluorophores with Absorption beyond 1000 nm for Biological Imaging in the Second Near-Infrared Subwindow

Small-molecule fluorescence imaging in the second near-infrared (NIR-II, 1000-1700 nm) window has gained increasing interest in clinical application. Till now, very few studies have been exploited in the small-molecule fluorophores with both excitation and emission in the NIR-II window. Inspired by the indocyanine green structure, a series of polymethine dyes with both absorption and emission in the NIR-II window have been developed for NIR-II imaging, providing the feasibility to directly compare optical imaging in the NIR-IIa (1300-1400 nm) subwindow under 1064 nm excitation with that in the NIR-II window under 808 nm excitation. The signal-background ratio and the tumor-normal tissue ratio achieved great improvement under 1064 nm excitation in the imaging of mouse blood pool and U87 glioma tumors. Our study not only introduces a broadband emission fluorophore for both NIR-II and NIR-IIa imaging, but also reveals the advantages of NIR-II excitation over NIR-I in in vivo imaging.