55526-70-0

Upstream product

• 15520-16-8 chloro-bis-(4-chloro-phenoxy)-phosphine 
• 106-48-9 4-chloro-phenol 
• 19081-37-9 4-chlorophenyl dichlorothiophosphate 

Downstream Products

• 15045-55-3 amidothiophosphoric acid O,O'-bis-(4-chloro-phenyl ester) 
• 92103-60-1 cyanocarbamimidoyl-thiophosphoramidic acid O,O'-bis-(4-chloro-phenyl) ester 

Relevant academic research and scientific papers

Dual substituent effects on anilinolysis of bis(aryl) chlorothiophosphates

The reactions of bis(Y-aryl) chlorothiophosphates (1) with substituted anilines and deuterated anilines are investigated kinetically in acetonitrile at 55.0 °C. The Hammett plots for substituent Y variations in the substrates show biphasic concave upwards

Kinetics and mechanism of the aminolysis of aryl phenyl chlorothiophosphates with anilines

(Chemical Equation Presented) Kinetic studies of the reactions of aryl phenyl chlorothiophosphates (1) and aryl 4-chlorophenyl chlorothiophosphates (2) with substituted anilines in acetonitrile at 55.0°C are reported. The negative values of the cross-interaction constant ρXY (ρXY = -0.22 and -0.50 for 1 and 2, respectively) between substituents in the nucleophile (X) and substrate (Y) indicate that the reactions proceed by concerted SN2 mechanism. The primary kinetic isotope effects (kH/kD = 1.11-1.13 and 1.10-1.46 for 1 and 2, respectively) involving deuterated aniline nucleophiles are obtained. Front- and back-side nucleophilic attack on the substrates is proposed mainly on the basis of the primary kinetic isotope effects. A hydrogen-bonded, four-center-type transition state is suggested for a front-side attack, while the trigonal bipyramidal pentacoordinate transition state is suggested for a back-side attack. The MO theoretical calculations of the model reactions of dimethyl chlorothiophosphate (1′) and dimethyl chlorophosphate (3′) with ammonia are carried out. Considering the specific solvation effect, the front-side nucleophilic attack can occur competitively with the back-side attack in the reaction of 1′.

The synthesis and evalution of novel aryl-substituted dithioimidophosphonates as an extrantant for metals

A novel series of O,O′,O″,O?- tetraaryldithioimidophonates [(ArO)2PS]2NH 4 were synthesized by the reaction of O,O,-diaryl phosphorochlorothionates 2 and diarylphosphonothioic amide under a strong basic condition. The key intermediat

Phase-Transfer Reactions of Phosphorus Thiochloride with Phenols in the System Liquid-Solid Phase

Preparative syntheses of aryl phosphorodichloridothioates and 2-propynyl phosphorodichloridothioates via phase-transfer reactions of phosphorus thiochloride with phenols in the presence of solid bases were developed.