55558-31-1Relevant academic research and scientific papers
REACTIVITE DES DERIVES DE CYCLOPROPYLIDENE-3 PROPYLE-I. SYNTHESE D'ALCOOLS β-CYCLOPROPYLIDENIQUES
Bertrand, M.,Leandri, G.,Meou, A.
, p. 1703 - 1710 (1981)
A series of β-cyclopropylidenic alcohols has been synthesized through the following sequence:(i) Wittig condensation between cyclopropylidenetriphenylphosphorane with appropriate monoprotected 1,3-dicarbonyl compounds; (ii)smooth hydrolysis of acetals (after necessary transacetalization step) and ketals thus formed; (iii) LAH reduction of aldehydes and ketones(yielding primary and secondery alcohols respectively) or treatment of ketones with methyllithium (yielding tertiary alcohols).
