55579-50-5

Basic information

• Product Name: 1,9(2H,10H)-Acridinedione, 7-chloro-3-(4-fluorophenyl)-3,4-dihydro-10-hydroxy-
• CAS NO: 55579-50-5
• Molecular Formula: C19H13ClFNO3
• Molecular Weight: 357.769
• Mol File: 55579-50-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,9(2H,10H)-Acridinedione, 7-chloro-3-(4-fluorophenyl)-3,4-dihydro-10-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,9(2H,10H)-Acridinedione, 7-chloro-3-(4-fluorophenyl)-3,4-dihydro-10-hydroxy-(55579-50-5)
• EPA Substance Registry System: 1,9(2H,10H)-Acridinedione, 7-chloro-3-(4-fluorophenyl)-3,4-dihydro-10-hydroxy-(55579-50-5)

Safety Data

• Hazardous Substances Data: 55579-50-5(Hazardous Substances Data)

Upstream product

• 55579-72-1 5-(4-fluoro-phenyl)-cyclohexane-1,3-dione 
• 552-89-6 2-nitro-benzaldehyde 

Relevant articles and documents

Synthesis and Antimalarial Properties of 1-Imino Derivatives of 7-Chloro-3-substituted-3,4-dihydro-1,9(2H,10H)-acridinediones and Related Structures

To improve upon the activity and properties of the 3-aryl-7-chloro-3,4-dihydro-1,9(2H,10H)-acridinediones, a variety of 1-imino derivatives (3) were prepared and shown to be highly active antimalarial agents in both rodents and primates.Among structural modifications prepared, including N10-alkyl and C2-substituted analogs, removal of the C9 oxygen, and introduction of an imino side chain at C9, the imines of the N10-H acridinediones were the most active compounds obtained.The imino derivative of7-chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione (9aa) proved to be highly active in advanced studies in primates.

10-Hydroxy-3,4-dihydroacridine-1,9(2H,10H)-diones: a new group of malaricidal and coccidiostatic compounds

2-Nitrobenzaldehydes and 1,3-cyclohexanediones condense in a mixture of hydrocholic acid and glacial acetic acid to 10-hydroxy-3,4-dihydroacridine-1,9(2H,10H)-diones. Many compounds of this group reveal a pronounced coccidiostatic and malaricidal effect i