55586-26-0

Basic information

• Product Name: 4-AMINO-3-HYDROXY-BENZONITRILE
• Synonyms: 4-AMINO-3-HYDROXY-BENZONITRILE
• CAS NO: 55586-26-0
• Molecular Formula: C₇H₆N₂O
• Molecular Weight: 134.14
• Mol File: 55586-26-0.mol
• Article Data: 15

Chemical Properties

• Melting Point: 149-150 °C
• Boiling Point: 314.103 °C at 760 mmHg
• Flash Point: 143.765 °C
• Appearance: /
• Density: 1.332 g/cm³
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.37±0.10(Predicted)
• CAS DataBase Reference: 4-AMINO-3-HYDROXY-BENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-3-HYDROXY-BENZONITRILE(55586-26-0)
• EPA Substance Registry System: 4-AMINO-3-HYDROXY-BENZONITRILE(55586-26-0)

Safety Data

• Hazardous Substances Data: 55586-26-0(Hazardous Substances Data)

Usage

用途

4-氨基-3-羟基-苯甲腈用作研究用化合物。

Upstream product

• 28177-79-9 2-nitro-6-cyanophenol 
• 7772-99-8 stannous chloride 
• 18495-15-3 3-hydroxy-4-nitrobenzonitrile 
• 873-62-1 m-cyanophenol 
• 33348-34-4 4-amino-3-iodobenzonitrile 

Downstream Products

• 183307-51-9 3-[(6-(2-amino-5-cyanophenoxy)-3,5-difluoro-4-methylpyridin-2-yl)oxy]-N,N-dimethylbenzamide 
• 98556-62-8 2-oxo-2,3-dihydro-1,3-benzoxazole-6-carbonitrile 
• 1397706-38-5 C₁₈H₁₇N₃O 
• 1362095-07-5 C₁₅H₁₂N₂OS 
• 211172-51-9 4-((2-ethoxy-3,4-dioxocyclobut-1-en-1-yl)amino)-3-hydroxybenzonitrile 
• 311311-27-0 N-(4-Cyano-2-hydroxyphenyl)-N'-(2-bromophenyl)thiourea 

Relevant articles and documents

Direct preparation of polyfunctional amino-substituted arylmagnesium reagents via an iodine-magnesium exchange reaction

The successive addition of PhMgCl and i-PrMgCl to functionalised iodoanilines allows their conversion to the corresponding amino-functionalised Grignard reagents, which react smoothly with a range of electrophiles in high yield.

High-Density and Thermally Stable Palladium Single-Atom Catalysts for Chemoselective Hydrogenations

Single-atom catalysts (SACs) have shown superior activity and/or selectivity for many energy- and environment-related reactions, but their stability at high site density and under reducing atmosphere remains unresolved. Herein, we elucidate the intrinsic driving force of a Pd single atom with high site density (up to 5 wt %) under reducing atmosphere, and its unique catalytic performance for hydrogenation reactions. In situ experiments and calculations reveal that Pd atoms tend to migrate into the surface vacancy-enriched MoC surface during the carburization process by transferring oxide crystals to carbide crystals, leading to the surface enrichment of atomic Pd instead of formation of particles. The Pd1/α-MoC catalyst exhibits high activity and excellent selectivity for liquid-phase hydrogenation of substituted nitroaromatics (>99 %) and gas-phase hydrogenation of CO2 to CO (>98 %). The Pd1/α-MoC catalyst could endure up to 400 °C without any observable aggregation of single atoms.

CONDENSED HETEROCYCLIC COMPOUND

A compound represented by the general formula (I) [R1 represents a C1-6 alkyl group, a halogen atom, or the like; A represents a phenylene group, or the like; X represents —CH(R3)—, —O—, —NH—, or the like; Y represents —O—, —NH—, —N═, or —S—; . . . represents a single bond or double bond; n represents 1 to 3; R2 represents a C1-6 alkyl group, a C1-6 alkoxy group, or the like; and R3 represents hydrogen atom, a C1-6 alkyl group, or the like], or a salt thereof which has a blood LDL cholesterol-reducing action, and is useful as an active ingredient of medicaments.