55591-35-0Relevant academic research and scientific papers
A new protocol for the preparation of aminals from aromatic aldehydes and their facile conversion to phosphonates
Dezfuli, Mohammad Karimi,Saidi, Mohammad Reza
, p. 89 - 96 (2007/10/03)
A new and fast method for the preparation of aminals is reported from the reaction of aromatic aldehydes and secondary amines in the presence of potassium carbonate in high yields. The aminal can be converted to the corresponding iminum salt in reaction with acetyl chloride very easily and in very short time with high yield. Addition of trialkylphosphite, as one possible nucleophile, to the prepared iminium salt produces the α-amino phosphonate in very high yield.
The Knoevenagel Reactions of Aldehydes with Carboxy Compounds. I. Reactions of p-Nitrobenzaldehyde with Active Methine Compounds
Tanaka, Mayumi,Oota, Osamu,Hiramatsu, Hideo,Fujiwara, Kazuyoshi
, p. 2473 - 2480 (2007/10/02)
The Knoenvenagel reactions of p-nitrobenzaldehyde (1) with β-keto acids, methylmalonic (2a) and α-methylacetoacetic acids (2b) were carried out in the presence of a tertiary amine such as pyridine.We have isolated the corresponding β-hydroxy intermediate
