556062-74-9Relevant academic research and scientific papers
Highly Selective β-Mannosylations and β-Rhamnosylations Catalyzed by Bis-thiourea
Li, Qiuhan,Levi, Samuel M.,Jacobsen, Eric N.
, p. 11865 - 11872 (2020)
We report highly β-selective bis-thioureas-catalyzed 1,2-cis-O-pyranosylations employing easily accessible acetonide-protected donors. A wide variety of alcohol nucleophiles, including complex natural products, glycosides, and amino acids were β-mannosylated and β-rhamnosylated successfully using an operationally simple protocol under mild and neutral conditions. Less nucleophilic acceptors such as phenols were also glycosylated efficiently in excellent yields and with high β-selectivities.
Direct and stereoselective synthesis of β-D-mannosides using 4,6-O-benzylidene-protected mannosyl diethyl phosphite as a donor
Tsuda, Toshifumi,Arihara, Ryoichi,Sato, Shinya,Koshiba, Miyuki,Nakamura, Seiichi,Hashimoto, Shunichi
, p. 10719 - 10733 (2007/10/03)
A direct and practical method for the construction of β-mannosidic linkages is described. While β-selectivities in the TMSOTf-promoted glycosidation of 2,3,4,6-tetra-O-benzyl-d-mannosyl diethyl phosphite are found to be highly dependent on the reactivity
