55610-89-4Relevant academic research and scientific papers
A simple and direct synthesis of erythro-β-amino-α-hydroxy esters from trans-β-phenylglycidic ester
Besbes, Rafaa,Ennigrou, Mohamed Rached
, p. 2185 - 2194 (2004)
trans-β-Phenylglycidic esters undergo ring opening when treated in tertbutyl alcohol with primary amines (R-NH2, with R = secondary group or tertiary group), which attacks epoxide exclusively at C-3 and avoids aminolysis of the ester group affording the erythro-β-amino-α-hydroxy esters as the sole product.
