55614-10-3

Basic information

• Product Name: ARG-PRO-LYS-PRO-GLN-GLN-PHE-TYR-GLY-LEU-MET-NH2
• Synonyms: L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Tyr-Gly-L-Leu-L-Met-NH2;[Tyr8] Substance P;RPKPQQFYGLM-NH2;(TYR8)-SUBSTANCE P;ARG-PRO-LYS-PRO-GLN-GLN-PHE-TYR-GLY-LEU-MET-NH2;H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-TYR-GLY-LEU-MET-NH2
• CAS NO: 55614-10-3
• Molecular Formula: C63H98N18O14S
• Molecular Weight: 1363.63
• Product Categories: Peptide
• Mol File: 55614-10-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: ARG-PRO-LYS-PRO-GLN-GLN-PHE-TYR-GLY-LEU-MET-NH2(CAS DataBase Reference)
• NIST Chemistry Reference: ARG-PRO-LYS-PRO-GLN-GLN-PHE-TYR-GLY-LEU-MET-NH2(55614-10-3)
• EPA Substance Registry System: ARG-PRO-LYS-PRO-GLN-GLN-PHE-TYR-GLY-LEU-MET-NH2(55614-10-3)

Safety Data

• Hazardous Substances Data: 55614-10-3(Hazardous Substances Data)

Usage

Uses

[Tyr8] Substance P is a neurotransmitter peptide associated with pain and depression as well as neurodegenerative diseases.

Relevant articles and documents

Synthesis and Radioiodination of Analogues of Substance P for the Building up of a Radioimmunoassay

The substance P (SP) analogs 3>-SP, 8>-SP, 8, Nle11>-SP and 1>-SP have been synthesized by classical methods of peptide synthesis as well as by the liquid phase peptide synthesis (LPPS) to allow conjugation with protein in the Nα-position and radioiodination. 8>-SP and 1>-SP have been radioiodinated by the chloramine T- and the lactoperoxidase method.A complete S-oxidation of SP was observed, when the chloramine T procedure was used, but this modification does not disturbe the assay.The introduction of the 1>-SP-tracer led to considerable improvements of our SP-radioimmunoassay.