55618-81-0Relevant academic research and scientific papers
NOVEL PHARMACEUTICALS
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Page/Page column 67, (2010/11/28)
The present invention relates to immune response modifiers of formula (I), which act selectively through agonism, of Toll-Like Receptors (TLRs), uses thereof, processes for the preparation thereof, intermediates used in the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including the treatment of infectious disease such as Hepatitis (e.g. HCV, HBV), genetically related viral infection and cancer.
Fused cycloalkylimidazopyridines
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, (2008/06/13)
[6,7]-propylene-, -butylene- or -pentylene-fused imidazopyridin-4-amines that induce interferon (α) biosynthesis in human cells. Also disclosed are pharmaceutical compositions containing such compounds and methods of inducing interferon (α) biosynthesis and treating viral infections involving the use of such compounds.
Retro-Ene Reactions in Heterocyclic Synthesis. II. A Facile Synthetic Method for 4-Hydroxy-2-pyridones
Ito, Kunio,Miyajima, Shingo
, p. 1037 - 1044 (2007/10/02)
Schiff's bases 1 derived from ketones and t-butylamine reacted with diphenyl malonate, diphenyl methylmalonate and diphenyl phenylmalonate to give 4-hydroxy-2-pyridones 4-6.Schiff's bases 1 on reaction with trimethyl methanetricarboxylate afforded 4-hydro
