55623-01-3

Upstream product

• 1609184-10-2 (R)-3,9-bis(2-nitrobenzenesulfonyl)-11-oxa-3,9-diazabicyclo[5.3.1]undec-7-ene 
• 1609184-09-9 (1R,7S)-3,9-bis(2-nitrobenzenesulfonyl)-11-oxa-3,9-diazabicyclo[5.3.1]undecan-7-ol 
• 1609184-08-8 (R)-7-methylene-1,5-bis((2-nitrobenzene)sulfonyl)-1,5-diazecan-3-ol 
• 1609184-07-7 (S)-N-glycidyl-N-(2-methylene-5-(2-nitrobenzenesulfonamido)pentyl)-2-nitrobenzenesulfonamide 
• 1609184-06-6 (S)-N-(5-(N-allyloxycarbonyl-2-nitrobenzenesulfonamido)-2-methylenepentyl)-N-glycidyl-2-nitrobenzenesulfonamide 
• 1609184-05-5 (S)-N-glycidyl-N-(5-hydroxy-2-methylenepentyl)-2-nitrobenzenesulfonamide 
• 1609184-04-4 (S)-N-(5-((tert-butyldimethylsilyl)oxy)-2-methylenepentyl)-N-glycidyl-2-nitrobenzenesulfonamide 
• 1071056-81-9 5-((tert-butyldimethylsilyl)oxy)-2-methylenepentan-1-ol 

Relevant academic research and scientific papers

Total synthesis of (-)-Lepistine

The first total synthesis of (-)-lepistine has been accomplished in 11 steps from (S)-glycidol. The synthesis features construction of the 10-membered ring via an intramolecular epoxide opening by nosylamide, regioselective dehydration to form an enol eth