55664-67-0Relevant academic research and scientific papers
2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE IN PHARMACEUTICS
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Page/Page column 39-40, (2008/06/13)
The invention relates to 2-thio-substituted imidazole derivatives of formula (I), wherein the radicals R1, R2, R3 and m have the meanings as cited in the description. The inventive compounds comprise an immunomodulatory action and/or an action that inhibits the release of cytokines and are thus suited for treating diseases associated with a disorder of the immune system.
Amino-substituted piperazine derivatives
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, (2008/06/13)
Amino-substituted piperazine derivatives of formula I STR1 wherein R1 -R6, X and Y are as defined in the description, and salts thereof, have properties inhibiting the biosynthesis of interleukin-1 (IL-1) as well as analgesic properties and can therefore be used as active ingredients in medicaments. They are prepared in a manner known per se.
Chemical compounds and processes
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, (2008/06/13)
Haloalkyl derivatives of aromatic compounds are prepared via reaction with dialkoxy or aralkoxy alkanes in the presence of a Lewis acid.
