55687-04-2Relevant academic research and scientific papers
Synthesis and biological evaluation of novel technetium-99m-labeled phenylquinoxaline derivatives as single photon emission computed tomography imaging probes targeting β-amyloid plaques in Alzheimer's disease
Iikuni, Shimpei,Ono, Masahiro,Tanimura, Keiichi,Watanabe, Hiroyuki,Yoshimura, Masashi,Saji, Hideo
, p. 20582 - 20590 (2017/04/21)
The development of an imaging probe targeting β-amyloid (Aβ) plaques in Alzheimer's disease labeled with technetium-99m, the most commonly used radioisotope for clinical diagnoses, has been strongly anticipated. In this study, we synthesized three novels
Antiviral agents
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Page/Page column 27; 28, (2016/05/02)
This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infections in mammals, as well as nove
RADIOACTIVE FLUORINE-LABELED QUINOXALINE COMPOUND
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Paragraph 0068-0069; 0144-0145, (2014/04/03)
Provided is a compound effective as a diagnostic imaging probe targeting amyloid and an agent for Alzheimer's disease diagnosis including the compound.
Structure-activity relationships and in vivo evaluation of quinoxaline derivatives for PET imaging of β-amyloid plaques
Yoshimura, Masashi,Ono, Masahiro,Matsumura, Kenji,Watanabe, Hiroyuki,Kimura, Hiroyuki,Cui, Mengchao,Nakamoto, Yuji,Togashi, Kaori,Okamoto, Yoko,Ihara, Masafumi,Takahashi, Ryosuke,Saji, Hideo
supporting information, p. 596 - 600 (2013/07/26)
This letter describes the synthesis, structure-activity relationships, and in vivo evaluation of a new series of 2-phenylquinoxaline (PQ) derivatives for imaging β-amyloid (Aβ) plaques in Alzheimer's disease (AD). In experiments in vitro, the affinity of
Antiviral agents
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, (2008/06/13)
This invention relates to compounds of formula I their salts, and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions comprising these compounds and their use in the treatment of picornavirus infections in mammals as well as novel
