55687-28-0

Basic information

• Product Name: 2-((4-Methoxy-2-nitrophenyl)aMino)acetic acid
• Synonyms: 2-((4-Methoxy-2-nitrophenyl)aMino)acetic acid;N-(4-Methoxy-2-nitrophenyl)glycine
• CAS NO: 55687-28-0
• Molecular Formula: C₉H₁₀N₂O₅
• Molecular Weight: 226.1861
• Mol File: 55687-28-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 492.2°C at 760 mmHg
• Flash Point: 251.5°C
• Appearance: /
• Density: 1.451g/cm³
• Vapor Pressure: 1.67E-10mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-((4-Methoxy-2-nitrophenyl)aMino)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4-Methoxy-2-nitrophenyl)aMino)acetic acid(55687-28-0)
• EPA Substance Registry System: 2-((4-Methoxy-2-nitrophenyl)aMino)acetic acid(55687-28-0)

Safety Data

• Hazardous Substances Data: 55687-28-0(Hazardous Substances Data)

Usage

General Description

2-((4-Methoxy-2-nitrophenyl)aMino)acetic acid, also known as 4-Methoxy-2-nitroaniline-2-carboxylic acid, is a chemical compound with a molecular formula C9H10N2O6. It is a derivative of 4-methoxy-2-nitroaniline and is commonly used in the synthesis of various pharmaceuticals and dyes. 2-((4-Methoxy-2-nitrophenyl)aMino)acetic acid is a yellow crystalline solid that is soluble in organic solvents such as ethanol and dimethyl sulfoxide. It is often used in organic chemistry research and is known for its ability to form stable complexes with metal ions. The compound has been studied for its potential applications in the field of medicinal chemistry and is considered an important intermediate in the production of various organic compounds.

InChI:InChI=1/C9H10N2O5/c1-16-6-2-3-7(10-5-9(12)13)8(4-6)11(14)15/h2-4,10H,5H2,1H3,(H,12,13)

Upstream product

• 79-08-3 bromoacetic acid 
• 96-96-8 4-methoxy-2-nitroaniline 
• 118807-82-2 (4-methoxy-2-nitro-phenylamino)-acetic acid ethyl ester 
• 118807-88-8 2-((4-methoxy-2-nitrophenyl)amino)acetonitrile 

Downstream Products

• 118807-82-2 (4-methoxy-2-nitro-phenylamino)-acetic acid ethyl ester 
• 55687-30-4 7-methoxyquinoxalin-2-ol 
• 55686-93-6 2-chloro-7-methoxyquinoxaline 
• 118807-93-5 5-Methoxy-1H-benzoimidazole 3-oxide 
• 357637-50-4 7-methoxy-5-(4-methoxy-benzyl)-5H-imidazo[1,5-a]quinoxalin-4-one 
• 357637-41-3 7-methoxy-1-(4-methoxy-benzyl)-1H-quinoxalin-2-one 

Relevant articles and documents

Synthesis and biological evaluation of quinoxaline derivatives as specific c-Met kinase inhibitors

A series of novel quinoxaline derivatives were synthesized and evaluated for their inhibitory activity against c-Met kinase enzyme. Most of the tested compounds exhibited potent inhibitory activity. All the synthesized quinoxaline compounds were further e

o-Nitroaniline Derivatives. Part 9. Benzimidazole N-Oxides Unsubstituted at N-1 and C-2

Since previous routes to the title compounds (1) have proved unsatisfactory as general methods, a simple new synthesis has been devised.N-Cyanomethyl-o-nitroanilines (5) are cyclised in basic media, giving 2-cyanobenzimidazole N-oxides (12) in good yield.Hydrolysis of these products with hydrochloric acid gives, directly, the title compounds as their hydrochloride salts (13), which may be isolated and purified, and which give the free N-oxides (1) by treatment with aqueous ammonia followed by evaporation. o-Nitrophenylglycine esters (4) may satisfactorily replace the nitriles (5) in certain cases.A modification of this kind in the related nitropyridylglycine series leads to 3H-imidazolpyridine 1-oxide (20).