55690-02-3Relevant articles and documents
Indolizy Carbene Ligand. Evaluation of Electronic Properties and Applications in Asymmetric Gold(I) Catalysis
Fensterbank, Louis,Forté, Jérémy,Gontard, Geoffrey,Lemière, Gilles,Martinez, Thibaut,Mouriès-Mansuy, Virginie,Troufflard, Claire,Vanitcha, Avassaya,Vanthuyne, Nicolas
, p. 19879 - 19888 (2021)
We report herein a new family of carbene ligands based on an indolizine-ylidene (Indolizy) moiety. The corresponding gold(I) complexes are easily obtained from the gold(I)-promoted cyclization of allenylpyridine precursors. Evaluation of the electronic pr
A copper-catalyzed domino reaction to construct functionalized indolizinones
Hu, Ben-Quan,Wang, Li-Xia,Shen, Gang,Tang, Ya-Lin,Yang, Luo
, p. 100097 - 100101 (2015)
An efficient copper-catalyzed domino reaction to 3,8a-disubstituted indolizinones has been firstly developed, and the protocol uses pyridine ketones and terminal alkynes as the starting materials, overriding the isolation of propargylic alcohols.
Straightforward Access to 2-Iodoindolizines via Iodine-Mediated Cyclization of 2-Pyridylallenes
Alahyen, Ismail,Fensterbank, Louis,Lemière, Gilles,Martinez, Thibaut,Mouriès-Mansuy, Virginie
supporting information, p. 817 - 821 (2020/07/14)
A metal-free access to 2-iodo-1,3-disubstituted indolizines has been developed. The proposed synthesis is relatively simple and efficient and involves the iodine-triggered 5-endo-trig cyclization of 2-pyridylallene precursors. While it can be conducted on
Palladium-catalyzed construction of poly-substituted indolizinones
Cho, Hanyang,Kim, Ikyon
experimental part, p. 5464 - 5480 (2012/09/08)
We have developed a highly efficient one-pot approach to poly-substituted indolizinones from tertiary propargylic alcohols by using a palladium-catalyzed domino reaction. This reaction is proposed to proceed via successive aminopalladation, reductive elim
Highly efficient synthesis of functionalized indolizines and indolizinones by copper-catalyzed cycloisomerizations of propargylic pyridines
Yan, Bin,Zhou, Yebing,Zhang, Hao,Chen, Jingjin,Liu, Yuanhong
, p. 7783 - 7786 (2008/03/12)
(Chemical Equation Presented) The copper-catalyzed cycloisomerizations of 2-pyridyl-substituted propargylic acetates and its derivatives are described, which offer an efficient route to C-1 oxygenated indolizines with a wide range of substituents under mild reaction conditions. The presented method could be readily applied to the synthesis of indolizinones through a cyclization/1,2- migration of tertiary propargylic alcohols.
