55694-05-8 Usage
Uses
Used in Pharmaceutical Industry:
2,4-Dichloro-5-[3,4,5-trimethoxybenzyl]pyrimidine is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the creation of complex molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-Dichloro-5-[3,4,5-trimethoxybenzyl]pyrimidine is employed as a building block in the development of new agrochemicals. Its incorporation into these compounds can lead to enhanced properties, such as increased effectiveness or reduced environmental impact.
Used in Research and Development:
2,4-Dichloro-5-[3,4,5-trimethoxybenzyl]pyrimidine is utilized as a research tool in the exploration of new drug and agrochemical candidates. Its biological activity and structural features make it a valuable component in the design and testing of novel compounds with potential applications in medicine and agriculture.
Check Digit Verification of cas no
The CAS Registry Mumber 55694-05-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,6,9 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 55694-05:
(7*5)+(6*5)+(5*6)+(4*9)+(3*4)+(2*0)+(1*5)=148
148 % 10 = 8
So 55694-05-8 is a valid CAS Registry Number.
55694-05-8Relevant articles and documents
Synthesis of functionalized diarylmethanes via a copper-catalyzed cross-coupling of arylmagnesium reagents with benzylic phosphates
Kofink, Christiane C.,Knochel, Paul
, p. 4121 - 4124 (2007/10/03)
A combination of copper chloride, triethyl phosphite, and tetrabutylammonium iodide is a very efficient catalytic system for the synthesis of polyfunctionalized diarylmethanes, using the cross-coupling reaction of arylmagnesium halides with benzylic phosphates. The antibiotic Trimethoprim has been prepared using this Cu(I)-catalyzed cross-coupling in 52% overall yield (four steps).
Metelation of diazines VIII metalation of 4-chloropyrimidine derivatives new synthesis of trimethoprim
Ple,Turck,Martin,Barbey,Queguiner
, p. 1605 - 1608 (2007/10/02)
A new synthesis of trimethoprim is described, metalation of a pyrimidine has been used in the key step. An exceptional regioselectivity in the metalation of pyrimidine derivatives has been highlighted.
