557086-54-1Relevant articles and documents
The first method for protection-deprotection of the indole 2,3-π bond
Baran, Phil S.,Guerrero, Carlos A.,Corey
, p. 1999 - 2001 (2003)
(Matrix presented) The scope and generality of a new reaction of indoles with MTAD is discussed. In most cases the ene-type reaction proceeds within seconds or minutes at 0°C to provide the urazole adducts in high yield. This reaction provides the first method for protecting the indole 2,3-double bond since the urazole adducts can be reconverted to the starting indole (retro-ene) simply by heating.