557091-48-2Relevant academic research and scientific papers
Reaction of 3,3-dichloro-2-dichloroacetylaminoacrylonitrile with amines
Pil'o,Brovarets,Romanenko,Drach
, p. 1724 - 1729 (2007/10/03)
Polychlorinated enamidonitrile Cl2C=C(CN)NHCOCHCl2 readily reacts with primary aromatic amines, dialkylamines, piperidine, and morpholine. The reaction is accompanied by complete elimination of chlorine atoms as chloride ions with formation of 4-cyanooxazoles having the corresponding amine residue in position 5 of the ring and a CH=N or diaminomethyl moiety in position 2. The structure of 5-arylamino-(dialkylamino)-4-cyano-2-formyloxazoles was confirmed by their acid hydrolysis, as well as by the condensation with phenylhydrazine, N-alkylrhodanines, and ethyl acetoacetate in the presence of urea.
