5571-06-2

Upstream product

• 18440-00-1 2-Hydroxy-4-methoxyphenyl 2-methoxybenzyl ketone 
• 75-11-6 diiodomethane 
• 96682-36-9 3-Hydroxymethyl-7,2'-dimethoxyisoflavanone 

Relevant academic research and scientific papers

Hydroxymethylation Studies of o-Hydroxyphenyl Benzyl Ketones with and without the use of Phase Transfer Catalyst: A Novel Synthesis of Isoflavanones

o-Hydroxyphenyl benzyl ketones, having a resorcinol unit in ring-A, on treatment with formalin in chloroform-aq. potassium carbonate biphase system give the corresponding α-hydroxymethyl derivatives.This reaction when carried out in the presence of a phas

A Convenient Phase Transfer Catalysed Synthesis of Isoflavanones

o-Hydroxyphenyl benzyl ketones (1, 4, 6, 8, 10, 12) on treatment with diiodomethane under phase transfer catalysed conditions in the presence of n-tetrabutylammonium iodide and sodium thiosulphate have been found to undergo smooth conversion into the corresponding isoflavanones (2, 5, 7, 9, 11, 13) in good yields (60-70percent).